The Effect of Soybean Protein on Bone Loss in a Rat Model of Postmenopausal Osteoporosis
スポンサーリンク
概要
- 論文の詳細を見る
This study was designed to investigate the modulatory effect of dietary soybean protein on the skeleton of an ovariectomized rat model with postmenopausal osteoporosis. Thirty-two female Sprague-Dawley rats were weight matched and divided into the following four experimental groups: Soy group, ovariectomized and fed soy protein diet; Estrogen group, ovariectomized, fed casein diet and injected with estrogen; Casein group, ovariectomized and fed casein diet; and Sham group, sham-operated and fed casein diet. The diets and estrogen were started two weeks after surgery, and continued for four weeks. Rats in the Sham, Soy and Estrogen groups had significantly higher (p<0.05) femur and tibia ash content than those in the Casein group. Accordingly, the calcium content of the tibia and femur were also significantly higher (p<0.05) in the Soy, Estrogen and Sham groups as compared to the Casein group. Serum total and bone-type alkaline phosphatase levels were both significantly lower (p<0.05) in the Estrogen and Sham groups in relation to the Soy and Casein groups. This study demonstrated that a 22% soybean protein diet could be just as effective as daily estrogen administration in suppressing bone loss due to ovariectomy. However, unlike estrogen, soy protein diet did not have any uterotrophic effect and did not decrease the markers of bone turnover measured, suggesting a possible difference in the mechanism of action.
- 財団法人 学会誌刊行センターの論文
著者
-
Yamamoto Shigeru
Department Of Biology Faculty Of Science Kyushu University
-
Adjei Andrew
Department Of Veterinary Science And Microbiology University Of Arizona
-
HARRISON Eric
Department of Adult Health, University of the Ryukyus, Okinawa
-
AMEHO Clement
Department of Pharmacology, Faculty of Medicine, University of the Ryukyus, Okinawa
-
KONO Shinzo
Department of Adult Health, University of the Ryukyus, Okinawa
-
ADJEI Andrew
Department of Bacteriology, University of the Ryukyus, Okinawa
関連論文
- Difructose Anhydride III Enhances Bioavailability of Water-Insoluble Iron in Anemic Vietnamese Women
- Effect of Protein and Energy Intakes on Body Composition in Non-Diabetic Maintenance-Hemodialysis Patients
- Validity of Physical Activity Indices for Adjusting Energy Expenditure for Body Size : Do the Indices Depend on Body Size?
- Nutritional Status of Lactating Mothers and Their Breast Milk Concentration of Iron, Zinc and Copper in Rural Vietnam
- Development and Validation of Food Frequency Questionnaire to Assess Calcium Intake in Postmenopausal Vietnamese Women
- Increased Nerve Growth Factor by Zinc Supplementation with Concurrent Vitamin A Deficiency Does Not Improve Memory Performance in Mice
- Suppressive Mechanisms of EPA on Human T Cell Proliferation
- Functional Results of Sleeve Lobectomy for Tuberculous Bronchial Stenosis
- Protein Deficiency Impairs DNA Vaccine-Induced Antigen-Specific T Cell but Not B Cell Response in C57BL/6 Mice
- Genistein Enhances Antigen-Specific Cytokine Production in Female DO11.10 Transgenic Mice
- Genistein Suppresses Development of Spontaneous Atopic-Like Dermatitis in NC/Nga Mice
- Deletion Polymorphisms in the Promoter Region of Fcγ Receptor IIB Is Not Associated with Antigen-Specific IgG2a and IgG2b Antibody Responses in NC/Nga Mice
- Defect in Toll-like Receptor-Mediated Activation in NC/Nga Mouse Macrophages
- Migration of a Subduroperitoneal Shunt Catheter into the Subdural Space : Case Report
- Effect of Citrus Fruit (Sudachi) Juice on Absorption of Calcium from Whole Small Fish in Healthy Young Men
- Japanese Citrus Fruit (Sudachi) Juice Is Associated with Increased Bioavailability of Calcium from Whole Small Fish and Suppressed Bone Resorption in Rats
- Further Evidence Regarding the Effect of Dietary Protein on Oral Tolerance against Beta-Lactoglobulin through Th1-Mediated Immune Response in Mice
- Low-Protein Diet Induces Oral Tolerance to Ovalbumin in Mice
- Effects of pH Variation and NaCl on In Vitro Digestibility of Cow's Milk Proteins in Commercially Available Infant Formulas
- Robust Motion Control Based on Quadratic Stabilization and Its Application to Two-Inertia Systems
- Expression of Vascular Endothelial Growth Factor Family Messenger RNA in Diseased Thyroid Tissues
- Expression of Vascular Endothelial Growth Factor (VEGF) Family Members in Breast Cancer
- Food Intake and Lipid Status of Three Vietnamese Populations with Different Incomes
- Metastatic Papillary Thyroid Carcinoma of the Submandibular Lymph Nodes with Extensive Squamous Metaplasia : Report of a Case
- Persistent Primitive Hypoglossal Artery Aneurysms : Report of Two Cases
- Endarterectomy for Persistent Primitive Hypoglossal Artery : Case Report
- Study on Factors of Body Image in Japanese and Vietnamese Adolescents
- Blood Pressure, Serum Cholesterol Concentration and Their Related Factors in Urban and Rural Elderly of Ho Chi Minh City
- The Polyphenol Content and Antioxidant Activities of the Main Edible Vegetables in Northern Vietnam
- STUDIES ON POLIOMYELITIS 1960-1961, IN FUKUOKA PREFECTURE, JAPAN
- Phagocytosis of Alveolar Macrophages after Conagenin Injection to Rats
- Soy Protein Hydrolyzate with Bound Phospholipids Reduces Serum Cholesterol Levels in Hypercholesterolemic Adult Male Volunteers
- Adenocarcinoma of the Pancreas Accompanied by Pancreatic Abscess
- Diffuse Large B-cell Lymphoma in the Ampulla of Vater Causing Obstructive Jaundice : Report of a Case
- Post Radiation Inflammatory Malignant Fibrous Histiocytoma Arising from the Chest Wall
- Treatment of Intraventricular Hemorrhage Using Urokinase
- RESTORATION OF PHOTOCHEMICAL ACTIVITY OF ISOLATED CHLOROPLASTS LOST BY ALUMINA TREATMENT
- Conagenin Derived from Streptomyces roseosporus Enhances Magcrophage Functions
- IgE Responses in Mice Fed Moderate Protein Deficient and High Protein Diets
- Stability Analysis for a Class of Interconnected Hybrid Systems
- Distribution and Immune Responses Resulting from Oral Administration of D-Limonene in Rats
- Differential intra-epithelial lymphocyte phenotypes following Cryptosporidium parvum challenge in susceptible and resistant athymic strains of mice
- The Effect of Soybean Protein on Bone Loss in a Rat Model of Postmenopausal Osteoporosis
- A Thermographic Determination of Tuberculin Reaction
- HYPOLIPIDEMIC EFFECTS OF CATECHOLESTROGEN AND 2-METHOXY-CATECHOLESTROGEN
- Nutrition during Pregnancy May Be Associated with Allergic Diseases in Infants
- Prospective ultrasonographic prediction of sentinel lymph node metastasis by real-time virtual sonography constructed with three-dimensional computed tomography-lymphography in breast cancer patients
- Search for Promotion Factors of Ultrasound Bone Measurement in Japanese Males and Pre/Post-Menarcheal Females Aged 8-14 Years
- Difructose Anhydride III Enhances Bioavailability of Water-Insoluble Iron in Anemic Vietnamese Women
- Trypsin Inhibitor Activity in Commercial Soybean Products in Japan.
- THE VIRULENCE TEST OF POLIVIRUSES USING THE PRIMARY HUMAN AMNION CELL AND THE EFFECTS OF THEIR INTRASPINAL INJECTION TO MICE
- STUDIES ON THE IN VITRO MARKER TEST OF ECHO VIRUSES
- Restriction Endonuclease Analysis of Varicella-Zoster Virus DNAs.
- Comparative analysis of herpes simplex virus type 1 mutants that are defective in fusion function by using restriction endonuclease.
- ANTIGENIC STUDIES ON TYPE 2 HERPES SIMPLEX VIRUSES BY NEUTRALIZATION KINETICS
- THERMOINACTIVATION OF HF AND M STRAINS OF HERPES SIMPLEX VIRUS IN VARIOUS CONDITIONS
- MUTANTS OF HERPES SIMPLEX VIRUS. I. ISOLATION AND PROPERTIES OF MUTANTS CHARACTERIZED BY PLAQUE SIZE AND CYTOPATHOGENICITY
- GENETIC ANALYSIS OF POLYKARYOCYTOSIS BY HERPES SIMPLEX VIRUS:I. EXPERIMENTS USING RECOMBINANTS FROM INTERTYPIC CROSS
- SEROLOGICAL STUDIES ON HERPES SIMPLEX VIRUSES BY NEUTRALIZATION KINETIC TEST
- A toxin released from variant stratins of Propionibacterium acnes isolated from patients with kawasaki disease.
- Natural Killer(NK) cell activity of mice treated with herpes simplex virus type-2, sarcoma-180 cells, cyclosporine and cimetidine.
- Nucleic Acids and/or Their Components: A Possible Role in Immune Function.
- STUDIES ON THE RELATIONSHIP BETWEEN VIRULENCE OF POLIOVIRUSES AND THEIR ANTIGENICITY
- ON THE EPIDEMIC OF INFLUENZA IN KURUME CITY, JAPAN, 1964
- Effect of a Glutamine-Supplemented Diet on Response to Methicillin-Resistant Staphylococcus aureus Infection in Mice.
- A Case of Zoster in the 2nd and 3rd Branches of the Trigeminal Nerve Associated with Simultaneous Herpes Labialis Infection. A Case Report.:A Case Report
- Enhanced growth of mycobacteria by culture filtrate of Gemella haemolysans.
- Two Novel Genes of Herpes Simplex Virus Type 1 Involved in Cell Fusion.
- The effect of cimetidine on survival of mice infected with herpes simplex virus type 2, murine encephalomyelitis virus and vesicular stomatitis virus infections.
- STUDIES ON SITES OF ACTION OF ANALGESICS:2. THE EFFECT OF ANALGESICS ON AFFERFNT PATHWAYS OF PAIN
- MUTANTS OF HERPES SIMPLEX VIRUS:II. IDU-RESISTANT MUTANTS AND A PRELIMINARY EXPERIMENT ON GENETIC RECOMBINATION
- Improvement of the Plaque Technique for Human Rotaviruses: Effect of Fetal Bovine Serum, Acetyltrypsin and Agar.:Effect of Fetal Bovine Serum, Acetyltrypsin and Agar
- Shedding of herpes simplex virus type 1 into saliva after surgery for oral and genital or urological cancer parients.
- THE EFFECT OF LSD AND RESERPINE ON THE CENTRAL NERVOUS SYSTEM OF THE CAT:THE ANTAGONISM BETWEEN LSD AND CHLORPROMAZINE OR RESERPINE