肉腫様の組織像を伴った肝細胞癌についての臨床的検討

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Thirty two autopsy cases with hepatocellular carcinoma (HCC) with sarcoma-like feature were analyzed and compared with those without during the past 17 years. The following clinical findings were suggestive of the sarcoma-like feature in HCC.<BR>1 Fever and evidence of lymphatic metastasis in the early stage of HCC with negative for serum AFP concentration.<BR>2 A metastatic-like appearance in abdominal angiogram with low serum AFP concentration.<BR>3 Progressive increase in tumor size with decreasing serum AFP levels after therapy.<BR>It is suspected that there exsists HCC with sarcoma-like feature among those with no response to the conventional therapy, especially transarterial embolization. We must consider the other therapeutic modalities for these cases on the definit diagnosis in thier life time.
社団法人日本肝臓学会の論文