胆管内に発育し閉塞性黄疸を呈した細小肝細胞癌の1例

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A case with minute hepatocellular carcinoma (HCC) who showed transient and recurrent obstructive jaundice due to tumor invasion into bile duct was reported.<BR>A 48 year-old male was admitted to our hospital with jaundice and upper abdominal pain. Laboratory examinations showed transient elevation of serum bilirubin, alkaline phosphatase and gammaglutanyl transpeptidase and normal AFP and CEA concentration. The surgical operation revealed that the minute HCC with polypoid growth was infiltrated into the bile duct.<BR>HCC may be present in many unusual ways. Jaundice occurs ussually due to the bile duct invasion in the terminal stage, and less commonly to the extension of HCC into a major hepatic bile duct. Although patients with minute HCC are usually anicteric and asymptomatic, jaundice was caused by intrahepatic biliary obstruciton from minute HCC in the present study. We thus report that the case was considered to be extremely rare.
社団法人日本肝臓学会の論文