Confirmation of the presence of lymph channels in hepatoma nodes for use in the treatment of hepatocellular carcinoma.

概要

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Four patients with hepatocellular carcinoma were injected with an adriamycin-Lipiodol emulsion (ADR-Lip) by direct puncture. In 3 of them, ADR-Lip helped to demonstrate the outline the lymph vessel running form the tumor to the coeliac lymph glands. This was confirmed by plain roentgrams and computed tomograms of the abdomen. Of the 3 patients, 2 were studied by collecting the lymph glands at necropsy or operation. A great number of foreign giant cells surrounding fat droplets of sizes which are considered Lipiodol were observed. Further, the administration of adreamycin at a dose level 3 to 5 times higher than the usual dose caused tumors to be markedly necrotized and reduced in size and alpha-fetoprotein levels to be maintained in a state of equilibration or decreased. Suggestion has been made that this therapy might be of value to patients not tolrating TAE.
社団法人日本肝臓学会の論文