新しいエコー下細径針組織生検法による肝細胞癌の組織診断とその意義

概要

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To make the definite diagnosis of small hepatocellular carcinoma (HCC), we performed US-guided fine needle aspiration biopsy originally deviced by Majima in 103HCC nodules between May. 1985 andNov. 1986. In conclusions; 1) 100% of 103 nodules in 96 cases were histologically confirmed as HCC nodules. 2) The incidence of well-diffenciated HCC increases with the reduction in size of the tumor, in marked contrast, the incidence of moderately or poorly differenciated HCC increases with the enlargement in size of the tumor. 3) Cytological and histological diagnosis were made at the same puncture, however positive rate of cytological diagnosis was only 35.6% in small HCC nodules less than 20mm in diameter. 4) 58.3% of HCC (from 11 to 15mm in diameter) were hyperechoic nodules, and 2 nodules (1.9%) were histologically confirmed as the natural necrotic nodules. 5) In this series, serious complications and skin metastases were not observed.