HUMAN NEUROPHYSINS DURING PREGNANCY, PUERPERIUM AND MENSTRUAL CYCLES
スポンサーリンク
概要
- 論文の詳細を見る
To clarify the hypothalamo-posterior pituitary function during pregnancy, puerperium and menstrual cycle, investigations were performed to determine the levels of serum neurophysins by specific radioimmunoassays. Sera from 75 women during normal pregnancy, 17 during postpartum and 49 during the normal menstrual cycle were assayed for Estrogen Stimulated Neuro-physin (ESN) and Nicotine Stimulated Neurophysin (NSN). ESN, associated with oxytocin increased during pregnancy and the values decreased to non-pregnant levels after parturition. During menstrual cycle ESN showed three peaks. In contrast, NSN, associated with vasopressin was little changed throughout the menstrual cycle, pregnancy and the puerperium. In this study two neurophysins changed independently, suggesting the hypothesis of “one hormone-one neurophysin.” The data also would indicate the availability of measurement of these two substances on the study of the function of human neurosecretory system.
著者
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Nagai Takashi
Department Of Animal Breeding And Reproduction National Institute Of Livestock And Grassland Science
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Iizuka Rihachi
Department Of Obstetrics And Gynecology School Of Medicine Keio University
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Iwashita Mitsutoshi
Department Of Obstetrics And Gynecology Kyorin University School Of Medicine
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YOKOKURA TSUNEO
Department of Obstetrics and Gynecology, School of Medicine, Keio University
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NAKAYAMA AKIHIKO
Department of Obstetrics and Gynecology, and Department of Pharmacology, School of Medicine
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OHNO TORANOSHIN
Department of Obstetrics and Gynecology, School of Medicine, Keio University
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Suzuki Hideaki
Department Of Cardiovascular Medicine Tohoku University Graduate School Of Medicine
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MAKINO TSUNEHISA
Department of Gynecology and Obstetrics, School of Medicine, Keio University
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OHNO TORANOSHIN
Department of Obstetrics and Gynecology School of Medicine, Keio University
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NAKAZAWA KAZUMI
Department of Obstetrics and Gynecology, and Department of Pharmacology, School of Medicine
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SUZUKI HIDEAKI
Department of Obstetrics and Gynecology, School of Medicine, Keio University
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NAGAI TAKASHI
Department of Obstetrics and Gynecology, School of Medicine, Keio University
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IIZUKA RIHACHI
Department of Obstetrics & Gynecology, School of Medicine, Keio University
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