Metformin Use in an Obese Diabetic Patient from Weeks 1 to 21 of Pregnancy.
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概要
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A 43-year-old diabetic woman was admitted in the 15th week of her first pregnancy. When HbAlc levels were 8.2%, we began diet therapy and continuous subcutaneous insulin infusion (CSII) therapy. The HbAlc levels subsequently ranged from 6.2 to 6.7%. She was delivered without complications of a healthy male infant (3120g) in the 38th week. Metformin was then administered. Six months later she was diagnosed as being in the 21st week of pregnancy. We changed from metformin to CSII therapy immediately. The HbAlc levels had ranged from 6.0 to 6.4% before the CSII therapy and from 5.8 to 6.3% after the CSII therapy during the entire second pregnancy. A macrosomia delivery (4070g) occurred in the 37th week. Although glycemic control was better during the 2nd pregnancy than the 1st pregnancy, metformin use until the 21st week may have induced macrosomia.
- 北関東医学会の論文
- 2005-02-01
著者
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Mori Masatomo
Department Of Medicine And Molecular Science Gunma University Graduate School Of Medicine
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Nagai Takashi
Department of Internal Medicine, Public Tomioka General Hospital
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Imamura Makoto
Department of Internal Medicine, Public Tomioka General Hospital
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Negishi Tetuo
Department of Internal Medicine, Public Tomioka General Hospital
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Nagai Takashi
Department Of Animal Breeding And Reproduction National Institute Of Livestock And Grassland Science
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Mori Masatomo
Department Of Internal Medicine And Molecular Science Graduate School Of Medicine Gunma University
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Negishi Tetuo
Department Of Internal Medicine Public Tomioka General Hospital
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Imamura Makoto
Department Of Internal Medicine Public Tomioka General Hospital
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Mori Masatomo
The First Department Of Internal Medicine
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IMAMURA Makoto
Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University
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