Subclinical Cushing's Disease Accompanied by Malignant Hypertension and Diabetes Mellitus
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概要
- 論文の詳細を見る
A 53-year-old woman was admitted because of hypertension and diabetes mellitus. Elevated diastolic blood pressure, hypertensive retinopathy and renal dysfunction indicated malignant hypertension. Adrenocorticotropic hormone (ACTH) and cortisol levels were high although there were no Cushingoid features.One mg dexamethasone administration decreased neither ACTH nor cortisol levels. Brain magnetic resonance imaging revealed a left pituitary tumor (7 mm × 6 mm). Upon removal, the tumor showed positive ACTH staining by immnohistochemistry, and was diagnosed as pituitary ACTH-secreting adenoma (Cushings disease). Her blood pressure, renal function, blood glucose and hormone levels subsequently improved. Malignant hypertension and deteriorated diabetes mellitus may have been due to subclinical Cushings disease.(Intrenal Medicine 41: 566-570, 2002)
- 社団法人 日本内科学会の論文
- 2002-07-01
著者
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Nagai Takashi
Department of Internal Medicine, Public Tomioka General Hospital
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Imamura Makoto
Department of Internal Medicine, Public Tomioka General Hospital
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IMAMURA Makoto
the Department of Internal Medicine, Public Tomioka General Hospital
-
Nagai Takashi
The Department Of Internal Medicine Public Tomioka General Hospital
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Misumi Shuuzou
The Department Of Neurosurgery Public Tomioka General Hospital
-
Imamura Makoto
Department Of Internal Medicine Public Tomioka General Hospital
-
Mori Masatomo
The First Department Of Internal Medicine
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