Seroconversion of Glutamic Acid Decarboxylase Antibodies in a Patient Initially Diagnosed as Having Type 2 Diabetes Mellitus
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概要
- 論文の詳細を見る
A 61-year-old man admitted in July 1998 had suffered from thirst, polydipsia and polyuria for three years. Diet and transient insulin therapy had induced good blood glucose control which was maintained by metformin hydrochloride for a year. Although it worsened, conventional insulin treatment re-implemented good blood glucose control. Glutamic acid decarboxylase antibodies (GAD-Ab) had been negative up to this point. After 8 months, blood glucose levels became elevated. To date, the GAD-Ab has been positive (112-120 U/ml), and the serum and urine C-peptide levels are decreased. Seroconversion of GAD-Ab should be noted in patients initially diagnosed as having GAD-Ab negative type 2 diabetes mellitus.
- 社団法人 日本内科学会の論文
- 2005-04-01
著者
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Mori Masatomo
Department Of Medicine And Molecular Science Gunma University Graduate School Of Medicine
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Nagai Takashi
Department of Internal Medicine, Public Tomioka General Hospital
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Imamura Makoto
Department of Internal Medicine, Public Tomioka General Hospital
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Nagai Takashi
Department Of Animal Breeding And Reproduction National Institute Of Livestock And Grassland Science
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Mori Masatomo
Department Of Internal Medicine And Molecular Science Graduate School Of Medicine Gunma University
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Imamura Makoto
Department Of Internal Medicine Public Tomioka General Hospital
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Mori Masatomo
The First Department Of Internal Medicine
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IMAMURA Makoto
Department of Applied Chemistry, Faculty of Science and Engineering, Chuo University
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