A Case of Adrenocortical Adenoma Producing 11-Deoxycorticosterone (DOC) Independent of ACTH Control.
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概要
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A 31-year-old woman with left adrenocortical adenoma had hypertension, hypokalemia and low plasma renin activity (PRA) level. The plasma aldosterone and urinary 17-OHCS levels were within normal range. However, the plasma 11-deoxycorticosterone (DOC) level was elevated. Diurnal variation of DOC was absent. Dexamethasone administration suppressed ACTH and cortisol levels, but did not depress DOC level. Acute synthetic ACTH administration increased cortisol level, however, DOC level was unchanged. After removal of the tumor, her blood pressure, serum potassium, PRA and DOC levels were normalized. The high level of DOC caused an increase in blood pressure and was independent of ACTH control.
- 北関東医学会の論文
著者
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Mori Masatomo
First Department Of Internal Medicine Gunma University School Of Medicine
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Nagai Takashi
Department Of Animal Breeding And Reproduction National Institute Of Livestock And Grassland Science
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Tomizawa Takashi
First Department Of Internal Medicine School Of Medicine Gunma University
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Satou Minoru
First Department of Internal Medicine, Gunma University School of Medicine
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Tomizawa Takashi
First Department of Internal Medicine, Gunma University School of Medicine
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