MECHANISM OF ACCUMULATION OF TAURINE IN THE HEART OF STARVED RATS
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概要
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The mechanism of increase of taurine concentration in the heart of starved rats was investigated. Starvation for 48 to 72 hr markedly increased the taurine level in heart muscle and serum. Adrenalectomy completely prevented the increase of taurine concentration in the heart during starvation. Incorporation of radioactive taurine into the heart tissue was increased in starved rats. Administration of phenoxybenzamine or propranolol prevented the increase of taurine concentration in heart and the enhanced transport of radioactive taurine during starvation. These observations indicate that adrenal factor, especially epinephrine, may be involved in regulation of cardiac taurine level.
- 社団法人 日本薬理学会の論文
著者
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Baba A
Laboratory Of Molecular Neuropharmacology
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Baba A
Osaka Univ. Osaka Jpn
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Baba Akemichi
サントリー生物医学研究所
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MATSUDA Toshio
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University
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Baba Akemichi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Osaka University
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Maeda Sadaaki
Department Of Pharmacology Faculty Of Dentistry Osaka University
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Iwata Heitaroh
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Osaka University
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Yamagami Satoru
Department Of Corneal Tissue Regeneration University Of Tokyo Graduate School Of Medicine
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MIZUI Takuzi
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University
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Matsuda Toshio
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Osaka University
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YAMAGAMI Satoru
Department of Pharmacology, Faculty of Pharmaceutical Sciences, Osaka University
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Matsuda Toshio
Department of Pharmacology
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MATSUDA Toshio
Department of Chemistry, Faculty of Science and Engineering,Ritsumeikan University
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