Vascular responsiveness of isolated and perfused simian metacarpal veins to several vasoconstrictor substances.
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概要
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Using the cannula inserting method, vascular responses to 7 vasoconstrictor substances were investigated on isolated, perfused simian metacarpal veins. The vein was markedly constricted by an intraluminal administration of norepinephrine, phenylephrine and 5-hydroxytryptamine with a maximal increase in perfusion pressure of over 100 mmHg. Clonidine and xylazine induced only a slight vasoconstriction, but tyramine produced no significant constriction. A large dose of KCI induced a strong vasoconstriction. In this study, it was demonstrated that the simian metacarpal vein has a specific characteristic of vascular reactivity.
- 公益社団法人 日本薬理学会の論文
著者
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Chiba Shigetoshi
Departmen T Of Pharmacology Shinshu University School Of Medicine
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ITO Takashi
Department of Advanced Materials Chemistry, Graduate School of Engineering, Yokohama National University
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