Colon Cancer Arising in an Ulcer Scar due to Intestinal Behçets Disease
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概要
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Neoplasms rarely arise in the intestinal lesion of Behçets disease. We present a 77-year-old man with Behçets disease who developed colon cancer in the ileocecal region. Ileocecal resection was performed and pathological examination of the specimen revealed advanced colon carcinoma (pT3, N1, M0). The lesion was associated with destroyed tunica muscularis and severe fibrosis suggesting a transmural ulcer scar (Ul-IVs). The p53 gene mutation analysis of the tumor showed a heterozygous deletion. This case indicates there is a possibility that cancer may develop in intestinal lesions of patients with Behçets disease as well as in those with other inflammatory bowel diseases.
著者
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SATO Katsuaki
Department of Applied Physics, Tokyo University of Agriculture and Technology
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Yamada Masayoshi
Department Of Electronics And Information Science Faculty Of Engineering And Design Kyoto Institute
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ARISAWA Tomiyasu
Department of Gastroenterology, Kanazawa Medical University
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HAYASHI Ranji
Department of Gastroenterology, Kanazawa Medical University
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SHIROEDA Hisakazu
Department of Gastroenterology, Kanazawa Medical University
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Arisawa Tomiyasu
Department of Gastroenterology, Kanazawa Medical University, Japan
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Tsutsumi Mikihiro
Department of Gastroenterology, Kanazawa Medical University
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Nomura Tomoe
Department of Gastroenterology, Kanazawa Medical University, Japan
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Yamada Masayoshi
Department of Gastroenterology, Kanazawa Medical University, Japan
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