Appropriate interruption of cetuximab may balance efficacy and toxicity: a case of long-term treatment with FOLFIRI plus cetuximab
スポンサーリンク
概要
- 論文の詳細を見る
A case of long-term treatment with FOLFIRI plus cetuximab was presented. A 77-year-old Japanese male was introduced FOLFIRI plus cetuximab as second line treatment. Although the CT revealed partial response, dermatologic adverse event was rather severe and eventually the case required cetuximab cessation. During the FOLFIRI without cetuximab period, CT evaluation revealed disease progression, but after the re-introduction of cetuximab, partial response was observed again. The course of this case would suggest the importance of appropriate cessation of cetuximab in order to balance the efficacy and toxicity, resulting in long treatment period like OPTIMOX strategy.
- 日本癌病態治療研究会の論文
著者
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Matsui Takanori
Department Of Gastroenterological Surgery Aichi Cancer Center Aichi Hospital
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Fujimitsu Yasunobu
Department Of Gastroenterological Surgery Aichi Cancer Center Aichi Hospital
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Yamada Tomohiro
Department Of Clinical Pathology Kinki University School Of Medicine
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Hirota Masashi
Department Of Biology Faculty Of Science Kochi University
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Uemura Takanori
Department Of Gastroenterological Surgery Aichi Cancer Center Aichi Hospital
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Sakamoto Junichi
Department Of Agricultural Chemistry Kyushu University
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Kojima Hiroshi
Department Of Clinical Oncology Ibaraki Prefectural Central Hospital
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Uemura Takanori
Department of gastroenterological surgery, Aichi cancer center Aichi hospital
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Fujii Yuka
Certified nurse in wound, ostomy and continence nursing, Aichi cancer center Aichi hospital
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Sakamoto Junichi
Department of Social-Life Science, Nagoya University Graduate School of Medicine
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