OE-091 Involvement of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) in Advanced Glycation End Products (AGE)/RAGE-Signaling Pathways(OE16,Diabetes (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

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概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2009-03-01

著者

• Ishibashi Toshiyuki

  First department of internal medicine, Fukushima Medical University

• Takeishi Yasuchika

  First department of internal medicine, Fukushima Medical University

• Kamioka Masashi

  First Department of Internal Medicine, Fukushima Medical University

• Sugimoto Koichi

  First Department of Internal Medicine, Fukushima Medical University

• Ohkawara Hiroshi

  First Department of Internal Medicine, Fukushima Medical University

• Sakamoto Nobuo

  First Department of Internal Medicine, Fukushima Medical University

• Takuwa Yo

  Department Physiology, Kanazawa University School of Medicine

• Takuwa Yo

  Department Of Molecular And Cellular Physiology Kanazawa University Graduate School Of Medical Scien

• Takeishi Yasuchika

  First Department Of Internal Medicine Fukushima Medical University

• Takeishi Yasuchika

  Department Of Cardiology And Hematology Fukushima Medical University

• Yamagishi Shouichi

  Department of Internal Medicine, Division of Cardio-Vascular Medicine, Kurume University

• ISHIBASHI Toshiyuki

  Department of Cardiology and Hematology, Fukushima Medical University

• SUGIMOTO Koichi

  Department of Cardiology and Hematology, Fukushima Medical University

• KAMIOKA Masashi

  Department of Cardiology and Hematology, Fukushima Medical University

• Ohkawara Hiroshi

  First Department Of Internal Medicine Fukushima Medical University

• Kamioka Masashi

  Department Of Cardiology And Hematology Fukushima Medical University

• Ishibashi Toshiyuki

  Department Of Cardiology And Hematology Fukushima Medical University

• Ishibashi Toshiyuki

  First Department Of Internal Medicine Fukushima Medical University

• Sugimoto Koichi

  Department Of Cardiology And Hematology Fukushima Medical University

• Ando Katsuya

  First Department of Internal Medicine, Fukushima Medical University

• Matsui Takanori

  Department of Pathophysiology and Therapeutics of Diabetic Vascular Complications, Kurume University

• Sakamoto Nobuo

  First Department Of Internal Medicine Fukushima Medical University

• Ando Katsuya

  First Department Of Internal Medicine Fukushima Medical University

• Sakamoto Keiji

  Department Of Cardiology Hoshi General Hospital

• Takeishi Yasuchika

  1st Dept. of Intern Med. Fukushima Medical University

• Sugimoto Koichi

  Cardiology Center Hoshi General Hospital

• Matsui Takanori

  Department Of Gastroenterological Surgery Aichi Cancer Center Aichi Hospital

• Matsui Takanori

  Department Of Pathophysiology And Therapeutics Of Diabetic Vascular Complications Kurume University

• Yamagishi Shouichi

  Department Of Pathophysiology And Therapeutics Of Diabetic Vascular Complications Kurume University

• Sugimoto Koichi

  First Department Of Internal Medicine Fukushima Medical University

• Sugimoto Koichi

  Department Of Cardiology Hoshi General Hospital

• Ishibashi Toshiyuki

  First Department Of Fumusima Medical University

• Takuwa Yo

  Department Of Cardiology

• Takeishi Yasuchika

  Department Of Advanced Cardiac Therapeutics Fukushima Medical University

関連論文

• OE-296 Metabolic Regulation of Coronary Vascular Tone : Role of Hydrogen Peroxide, Adenosine 5'-diphosphate, and Angiotensin(OE50,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (English),The 73rd Annual Scientific M
• PE-388 Atorvastatin Blocks an Advanced Glycation End Products (AGE) : Receptor for AGE(RAGE) Axis in Diabeteic Vascular Responses(Cardiovascular pharmacology, basic/clinical(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese
• PE-086 New Insights into Oxidized LDL-induced RhoA and Rac1 Activation by an LOX-1-MT1-MMP Axis in Endothelial Dysfunction(Endothelium(02)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Attenuation of Diastolic Heart Failure and Life-Threatening Ventricular Tachyarrhythmia After Peripheral Blood Stem Cell Transplantation Combined With Cardioverter-Defibrillator Implantation in Myeloma-Associated Cardiac Amyloidosis
• DPJ-072 Regulation of Coronary Vascular Tone via Redox Modulation in the Alpha1-Adrenergic-Angiotensin-Endothelin Axis of the Myocardium(DPJ12,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Digital Poster Session (Japanese),The 73rd
• Combination of Heart-Type Fatty Acid Binding Protein and Brain Natriuretic Peptide Can Reliably Risk Stratify Patients Hospitalized for Chronic Heart Failure
• OE-183 Clinical Importance of Serum Heart-type Fatty Acid Binding Protein Levels in Heart Failure Patients : Comparisons with Sympathetic Nervous Activity(Heart Failure, Clinical 1 (M) : OE22)(Oral Presentation (English))
• OE-022 Prognostic Importance of ^I-MIBG Dynamic SPECT In Patients with Chronic Heart Failure(Nuclear Cardiology 1 (I) : OE3)(Oral Presentation (English))
• Increased Serum Levels of H-FABP in Patients with Severe Congestive Heart Failure
• ^I-MIBG Dynamic SPECT in Patients with Congestive Heart Failure
• Direct Evidence that Sustained Dysfunction of Left Atrial Appendage Contributes to the Occurrence of Cardiogenic Brain Embolism in Patients with Paroxysmal Atrial Fibrillation
• Aortic Atherosclerosis and Abnormalities of Blood Flow Conditions Are Important as Risk Factor for Ischemic Stroke in Non-Valvular Atrial Fibrillation
• Aortic Vortex Flow Represented by Contrast Echography Is a Useful Tool to Visualize Blood Viscosity in Acute Cerebral Embolism
• Ongoing myocardial damage relates to cardiac sympathetic nervous disintegrity in patients with heart failure
• Combination of conventional biomarkers for risk stratification in chronic heart failure
• PJ-779 8-Hydroxy-2'-Deoxyguanosine Predicts Adverse Clinical Outcomes in Patients with Heart Failure(PJ131,Heart Failure (Laboratory/Biomarkers) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Risk Stratification of Chronic Heart Failure Patients by Multiple Biomarkers : Implications of BNP, H-FABP, and PTX3
• PJ-779 8-Hydroxy-2'-Deoxyguanosine Predicts Adverse Clinical Outcomes in Patients with Heart Failure(PJ131,Heart Failure (Laboratory/Biomarkers) 2 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Diminution of angiotensin II-induced contraction of the abdominal aorta isolated from Watanabe heritable hyperlipidemic rabbits
• A Role for Signal Transducer and Activator of Transcription 3, Mitogen-Activated Protein Kinases, and Akt for Cardiac Phenotypes in Vivo
• Pressure and Volume Overload-Induced Cardiac Hypertrophy Is Associated with Distinct Activation of Signal Transduction Pathways
• Artial Enlargement Induced by Volume Overload Is Associated with Altenations of Wnt Signaling Proteins
• Comparison of Nitric Oxide Production in Response to Carbachol Between Macrovascular and Microvascular Cardiac Endothelial Cells
• Protein kinase C-Calcineurin pathway is Involved in Insulin-Like Growth Factor-1-Induced Hypertrophy of Cultured Adult Rat Ventricular Myocytes
• Role of Calcineurin in Insulin-Like Growth Factor-1-Induced Hypertrophy of Cultured Adult Rat Ventricular Myocytes
• PE-493 Rapid Improvement of Impaired Endothelium-Dependent Vasodilation and Rac1/NADPH Oxidase-Derived ROS Generation in Vivo by Pravastatin(PE083,Cardiovascular Pharmacology (Basic), Cost-health Care System/DPC/Laws (H),Poster Session (English),The 73rd
• OE-091 Involvement of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) in Advanced Glycation End Products (AGE)/RAGE-Signaling Pathways(OE16,Diabetes (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-664 LOX-1 plays a crucial role in RhoA-and Rac1-dependent signaling through Gi induced by oxidized low-density lipoprotein in endothelial cells(Molecular biology, vascular-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-559 Pravastatin Rapidly Prevents Thrombin-induced Vasoconstriction and NADPH Oxidase-dependent ROS Generation in vivo : Implications for Beneficial Effect(Cardiovascular pharmacology, basic/clinical-5, The 71st Annual Scientific Meeting of the Japanese
• PJ-216 Receptor for Advanced Glycation End Products (RAGE) Plays a Crucial Role in Atherosclerosis(Atherosclerosis, basic-9, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-067 New Insights into Regulation of Diabetic Vascular Remodeling by an MT1-MMP-RAGE axis(Atherosclerosis, basic-8, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-197 RhoA-Dependent PAI-1 Gene Exprssion Induced in Endothelial Cells by Monocyte Adhesion is Mediated Via Geranylgeranyl Transferase I and Ca^ Signaling(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• PJ-475 Crucial Role of Geranylgeranyl Transferase I in AGE-Induced Gene Expression in Diabetes(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-473 A Novel Role of LOX-1 in Monocyte Adhesion-Induced Gene Expression via Redox-Sensitive and Ca^ Signaling Pathways in Endothelial Cells(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of
• PJ-102 MT1-MMP-RAGE Axis in Regulation of Advanced Glycation End Products (AGEs)-Dependent Redox-sensitive Signaling(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulatio
• PE-003 Increased Expression of Matrix Metalloproteinase-9 and Apoptosis Induced by Advanced Glycation Endproducts in Type 2 Diabetes : Implications for Plaque Instability(Acute coronary syndrome, basic/clinical-4 (IHD) PE1,Poster Session (English),The 70t
• OJ-262 A Role of Reactive Oxygen Species in Coronary Spasm(Coronary circulation, basic/clinical-2 (IHD) OJ44,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-164 Essential Role of Rapid Geranylgeranylation from Unprocessed RhoA in RhoA Activation and Increase in Unprocessed RhoA in Atherosclerosis(Endothelium-2 (H) OJ28,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japan
• Monocyte Adhesion to Endothelial Cells Activates p47phox/NF-kB via Renin-Angiotensin System(RAS), Resulting in Gene Induction of MCP-1, ICAM-1 and Tissue Factor (Atherosclerosis, Basic 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulatio
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• Blockade of Renin-angiotensin System (RAS) Inhibits Oxidized LDL-induced Superoxide Generation by Suppressing NADPH Oxidase Component Nox-4, p47 phox and Rac(Atherosclerosis, Basic 8 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation So
• Membrane type 1 Metalloproteinase (MT1-MMP) is Involved in the RhoA-dependent eNOS Downergulation Induced by Oxidized LDL in Endothelial Cells(Atherosclerosis, Basic 4 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Mast Cells Contribute to Flow Restoration by Bone Marrow Cell Transplantation in Rats With Ischemic Limbs
• Role of Ca^ Influx in Tissue Factor Expression in Monocyte Adhesion to Endothelial Cells
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• Therapeutic Effect of Intravenous Administration of Statin on eNOS Downregulation and ROS Generation in Response to Thrombin in Vivo(Cardiovascular Pharmacology, Basic/Clinical 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-582 Intravenous administration of statin prevents RhoA activation-triggered eNOS downregulation and reactive oxygen species induced by thrombin in rats(Cardiovascular Pharmacology, Basic/Clinical 5 (H) : PJ98)(Poster Session (Japanese))
• PE-216 Mechanism and Role of Geranylgeranylation in RhoA Activation in Endothelial Dysfunction(Metabolism/Biochemistry/Energetics 1 (IHD) : PE37)(Poster Session (English))
• OE-118 Inhibition of Matrix Metalloproteinases (MMPs) Suppresses the RhoA-dependent eNOS Downergulation Induced by Oxidized LDL in Endothelial Cells(Atherosclerosis, Basic 1 (IHD) : OE14)(Oral Presentation (English))
• Rho Activation and Extracellular Signal-Regulated Kinase (ERK) Downregulation Are Crucial for eNOS Downregulation in Monocyte Adhesion to Endothelial Cells
• Thrombin-lnduced Downregulation of Endothelial Nitric Oxide Synthase (eNOS) via Rho Activation in Human Endothelial Cells :Involvement of Geranylgeranyl Transferase Activation
• Thrombin-Stimulated Ca^ Signaling Mediated via RhoA Activationin Tissue Factor (TF) and Plasminogen Activator Inhibitor-1 (PAI-1) Synthesis in Endothelial Cells
• RhoA Activation Plays an Integral Role in Tissue Factor (TF) Gene Expression
• Oxidized LDL Downregulates Endothelial Nitric Oxide Synthase (eNOS) via Rapid RhoA Activaion in Endothelial Cells
• RELATIONSHIP OF THALLIUM-201 DEFECT AND LEFT VENTRICULAR FUNCTION AFTER DIPYRIDAMOLE INFUSION
• Quantitative Assessment of Myocardial ^Tc-sestamibi Uptake During Exercise : Usefulness of Response Rate for Assessing Severity of Coronary Artery Disease
• OE-073 Quantitative Analysis of Change in Early Diastolic Strain Rate for Adenosine-Induced Myocardial Dysfunction(OE13,Echo/Doppler (New Technology) (I),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Impaired myocardial fatty acid metabolism detected by ^I-BMIPP in patients with unstable angina pectoris: Comparison with perfusion imaging by ^Tc-sestamibi
• PE-322 SPECT/CTCA Fusion Image is Useful for the Diagnosis of Coronary Artery Stenosis with Calcification(PE054,CT/MRI (New Technology) (I),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• DPJ-024 Serum NT-proBNP Level for Diagnosis of Diastolic Heart Failure in Japanese Population(DPJ04,Heart Failure (Diagnosis) (M),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-027 Adaptive Servo Ventilation Improves Cardiac Function in Heart Failure Patients with Cheyne-Stokes Respiration(OE05,Obesity/SAS (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Role of Advanced Glycation End Products (AGEs) in Increased Matrix Metalloproteinases (MMPs) Expression in Patients with Diabetes Mellitus (DM)(Diabetes/Obesity 9 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-039 Correlation between Atherosclerotic Plaque Instability and Matrix Metalloproteinase(MMPs) Expression in Autopsy Cases of Diabetes Mellitus(DM)(Diabetes/Obesity 1 (H) : OJ5)(Oral Presentation (Japanese))
• Dynamic ^I-MIBG SPECT reflects sympathetic nervous integrity and predicts clinical outcome in patients with chronic heart failure
• PE-429 Phosphorylation-independent regulation in cell distribution of signal transducer and activator of transcription (stat) in hypertrophied rabbit heart.(Cardiomyopathy, Basic and Clinical 1 (M) : PE73)(Poster Session (English))
• PE-321 A Pivotal Involvement of Toll-like Receptor-2 in the Pathogenesis of Cuff Induced Vascular Injury(Atherosclerosis, Basic 5 (IHD) : PE55)(Poster Session (English))
• PE-203 AT-1 Receptor Blockade Prevents Cardiac Hypertrophy through Inhibiting Protein Kinase C ε and Extracellular Signal-regulated Kinase in Renal Failure.(Kidney/Renal Circulation 1 (H) : PE35)(Poster Session (English))
• PE-005 Induction of atrial tachyarrythmia was associated with down-regulation of connexin family in dilated left atrium by volume overload(Arrhythmia, Basic 2 (A) : PE1)(Poster Session (English))
• OJ-532 Pitavastatin Inhibits Cardiac Hypertrophy in Rat Model of Progressive Renal Injury through Preventing the Activation of Extracellular-signal Regulated Kinase (ERK)(Kidney/Renal Circulation 3 (H) : OJ65)(Oral Presentation (Japanese))
• PJ-833 Assessment of Left Atrial Function : Comparison of MDCT and Echocardiography(CT / DSA(11)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-248 Regulation of Coronary Vascular Tone via Redox Modulation in the Alpha-Adrenergic-Angiotensin-Endothelin Axis of the Myocardium(Coronary circulation, basic/clinical(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
• PJ-217 Monocyte Adhesion Induces Gene Expression Mediated via LOX-1-dependent Signaling Pathways in Endothelial Cells(Atherosclerosis, basic-9, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
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• IS112 Granulocyte-macrophage colony-stimulating factor alters cellular and extracellular composition of atherosclerotic lesions and reduces atherosclerosis in atherogenic rabbits
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• OJ-217 Role of geranylgeranyl transferase activation and Ca^ Signaling in Plasminogen Activator Inhibitor-1 Expression in Endothelial Cells Triggered by Monocyte Adhesion(Blood Coagulation/Fibrinolysis (IHD) : OJ24)(Oral Presentation (Japanese))
• OJ-049 Nicorandil Suppresses Thrombin-induced Tissue Factor (TF) and Plasminogen Activator Inhibitor-1 Expression (PAI-1) via Blockade of Ca^ influx in Endothelial Cells(Antithrombofic Ttherapy (H) : OJ6)(Oral Presentation (Japanese))
• OE-274 HMG-CoA Reductase Inhibitor (Statin) Possibly Functions as Ca^ Antagonist in Endothelial Cells(Cardiovascular Pharmacology, Basic/Clinical 1 (H) : OE34)(Oral Presentation (English))
• Blockade of Renin-Angiotensin System Downregulates TF in Monocyte Adhesion to Endothelial Cells via Suppressing ICAM-1, MCP-1 Expression and Ca^ Signaling
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