Monocyte Adhesion to Endothelial Cells Activates p47phox/NF-kB via Renin-Angiotensin System(RAS), Resulting in Gene Induction of MCP-1, ICAM-1 and Tissue Factor (Atherosclerosis, Basic 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulatio

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概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2005-03-01

著者

• Ishibashi Toshiyuki

  First department of internal medicine, Fukushima Medical University

• Maruyama Yukio

  First Department of Internal Medicine, Fukushima Medical University

• Kamioka Masashi

  First Department of Internal Medicine, Fukushima Medical University

• Sugimoto Koichi

  First Department of Internal Medicine, Fukushima Medical University

• Ohkawara Hiroshi

  First Department of Internal Medicine, Fukushima Medical University

• Sakamoto Nobuo

  First Department of Internal Medicine, Fukushima Medical University

• KAMIOKA Masashi

  Department of Cardiology and Hematology, Fukushima Medical University

• Ohkawara Hiroshi

  First Department Of Internal Medicine Fukushima Medical University

• Kamioka Masashi

  Department Of Cardiology And Hematology Fukushima Medical University

• Ishibashi Toshiyuki

  First Department Of Internal Medicine Fukushima Medical University

• Sugimoto Koichi

  Department Of Cardiology And Hematology Fukushima Medical University

• Sakamoto Takayuki

  First Department of Internal Medicine, Fukushima Medical University

• Maruyama Yukio

  First Department Of Internal Medicine Fukushima Medical University

• Sakamoto Nobuo

  First Department Of Internal Medicine Fukushima Medical University

• Maruyama Yukio

  First Department Of Internal Medicine Fukushima Medical College

• Sugimoto Koichi

  Cardiology Center Hoshi General Hospital

• Sakamoto Takayuki

  First Department Of Internal Medicine Fukushima Medical University

• Sugimoto Koichi

  First Department Of Internal Medicine Fukushima Medical University

• Sugimoto Koichi

  Department Of Cardiology Hoshi General Hospital

• Ishibashi Toshiyuki

  First Department Of Fumusima Medical University

関連論文

• OE-296 Metabolic Regulation of Coronary Vascular Tone : Role of Hydrogen Peroxide, Adenosine 5'-diphosphate, and Angiotensin(OE50,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (English),The 73rd Annual Scientific M
• Attenuation of Cardioprotective Effect by Postconditioning in Coronary Stenosed Rat Heart and Its Restoration by Carvedilol
• PJ-294 Quantitative Analysis of Change in Early Diastolic Strain Rate for Exercise Induced Myocardial Ischemia: Comparison with TC^ Myocardial Scintigraphy(Echo/Doppler(14)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
• PE-533 Short-term Cholesterol-lowering Therapy Improves Myocardial Microvascular Dysfunction in Patients with Hypercholesterolemia : Evaluation of Myocardial Blood Velocity by Myocardial Contrast Echocardiography(Echo/Doppler(10)(I),Poster Session(English
• PE-388 Atorvastatin Blocks an Advanced Glycation End Products (AGE) : Receptor for AGE(RAGE) Axis in Diabeteic Vascular Responses(Cardiovascular pharmacology, basic/clinical(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese
• PE-086 New Insights into Oxidized LDL-induced RhoA and Rac1 Activation by an LOX-1-MT1-MMP Axis in Endothelial Dysfunction(Endothelium(02)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-248 New Developed Powerful Tool for Detecting of Exercise Induced Myocardial Dysfunction : Assessment of Early Diastolic Strain Rate(Echo / Doppler(04)(I),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
• Attenuation of Diastolic Heart Failure and Life-Threatening Ventricular Tachyarrhythmia After Peripheral Blood Stem Cell Transplantation Combined With Cardioverter-Defibrillator Implantation in Myeloma-Associated Cardiac Amyloidosis
• Prediction of Remote Left Ventricular Volumes and Functions After Acute Myocardial Infarction With Successful Coronary Intervention
• DPJ-072 Regulation of Coronary Vascular Tone via Redox Modulation in the Alpha1-Adrenergic-Angiotensin-Endothelin Axis of the Myocardium(DPJ12,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Digital Poster Session (Japanese),The 73rd
• Unexpected Worsening of Mitral Regurgitation After Surgical Closure of Atrial Septal Defect
• Involvement of von Willebrand Factor and PGI_2 in Platelet Binding to a Partially Denuded Endothelial Monolayer
• RhoA and Rac1 Changes in the Atherosclerotic Lesions of WHHLMI Rabbits
• PE-493 Rapid Improvement of Impaired Endothelium-Dependent Vasodilation and Rac1/NADPH Oxidase-Derived ROS Generation in Vivo by Pravastatin(PE083,Cardiovascular Pharmacology (Basic), Cost-health Care System/DPC/Laws (H),Poster Session (English),The 73rd
• OE-091 Involvement of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) in Advanced Glycation End Products (AGE)/RAGE-Signaling Pathways(OE16,Diabetes (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-664 LOX-1 plays a crucial role in RhoA-and Rac1-dependent signaling through Gi induced by oxidized low-density lipoprotein in endothelial cells(Molecular biology, vascular-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-559 Pravastatin Rapidly Prevents Thrombin-induced Vasoconstriction and NADPH Oxidase-dependent ROS Generation in vivo : Implications for Beneficial Effect(Cardiovascular pharmacology, basic/clinical-5, The 71st Annual Scientific Meeting of the Japanese
• PJ-216 Receptor for Advanced Glycation End Products (RAGE) Plays a Crucial Role in Atherosclerosis(Atherosclerosis, basic-9, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-067 New Insights into Regulation of Diabetic Vascular Remodeling by an MT1-MMP-RAGE axis(Atherosclerosis, basic-8, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-197 RhoA-Dependent PAI-1 Gene Exprssion Induced in Endothelial Cells by Monocyte Adhesion is Mediated Via Geranylgeranyl Transferase I and Ca^ Signaling(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• PJ-475 Crucial Role of Geranylgeranyl Transferase I in AGE-Induced Gene Expression in Diabetes(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-473 A Novel Role of LOX-1 in Monocyte Adhesion-Induced Gene Expression via Redox-Sensitive and Ca^ Signaling Pathways in Endothelial Cells(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of
• PJ-102 MT1-MMP-RAGE Axis in Regulation of Advanced Glycation End Products (AGEs)-Dependent Redox-sensitive Signaling(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulatio
• PE-003 Increased Expression of Matrix Metalloproteinase-9 and Apoptosis Induced by Advanced Glycation Endproducts in Type 2 Diabetes : Implications for Plaque Instability(Acute coronary syndrome, basic/clinical-4 (IHD) PE1,Poster Session (English),The 70t
• OJ-262 A Role of Reactive Oxygen Species in Coronary Spasm(Coronary circulation, basic/clinical-2 (IHD) OJ44,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-164 Essential Role of Rapid Geranylgeranylation from Unprocessed RhoA in RhoA Activation and Increase in Unprocessed RhoA in Atherosclerosis(Endothelium-2 (H) OJ28,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japan
• Monocyte Adhesion to Endothelial Cells Activates p47phox/NF-kB via Renin-Angiotensin System(RAS), Resulting in Gene Induction of MCP-1, ICAM-1 and Tissue Factor (Atherosclerosis, Basic 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulatio
• Activation of CCR2 by MCP-1 Accelerates TF Expression via Ca2+ Influx in Monocyte Adhesion to Nitric Oxide (NO)-Impaired Endothelial Cells(Atherosclerosis, Basic 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Blockade of Renin-angiotensin System (RAS) Inhibits Oxidized LDL-induced Superoxide Generation by Suppressing NADPH Oxidase Component Nox-4, p47 phox and Rac(Atherosclerosis, Basic 8 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation So
• Membrane type 1 Metalloproteinase (MT1-MMP) is Involved in the RhoA-dependent eNOS Downergulation Induced by Oxidized LDL in Endothelial Cells(Atherosclerosis, Basic 4 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Difference in Early Effects of Statin Therapy on Coronary and Forearm Flow Reserve in Postmenopausal Hypercholesterolemic Women
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• P433 CORONARY MICROVASCULAR FUNCTION AND THALLIUM-201 SPECT FINDINGS IN PATIENTS WITH EXERCISE INDUCED ISCHEMIC ST CHANGES BUT NORMAL CORONARY ARTERIES
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• Role of Ca^ Influx in Tissue Factor Expression in Monocyte Adhesion to Endothelial Cells
• Vasoconstrictive Response in the Vascular Beds of the Non-Exercising Forearm During Leg Exercise in Patients With Mild Chronic Heart Failure
• PJ-711 Antioxidant and Anti-hypertrophic Effects of Carbon Monoxide is Mediated via the Suppression of Akt Activation in Angiotensinlltreated LDL-receptor Knockout Mice(Vascular smooth muscle-2, The 71st Annual Scientific Meeting of the Japanese Circulati
• Inhibition of Matrix Metalloproteases (MMPs) Suppresses Rac/NADPH Oxidase-derived Reactive Oxygen Species (ROS) Generation in Oxidized Low Density Lipoprotein-stimuleted Endothelial Cells(Atherosclerosis, Basic 4 (IHD), The 69th Annual Scientific Meeting
• Therapeutic Effect of Intravenous Administration of Statin on eNOS Downregulation and ROS Generation in Response to Thrombin in Vivo(Cardiovascular Pharmacology, Basic/Clinical 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
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• PE-216 Mechanism and Role of Geranylgeranylation in RhoA Activation in Endothelial Dysfunction(Metabolism/Biochemistry/Energetics 1 (IHD) : PE37)(Poster Session (English))
• OE-118 Inhibition of Matrix Metalloproteinases (MMPs) Suppresses the RhoA-dependent eNOS Downergulation Induced by Oxidized LDL in Endothelial Cells(Atherosclerosis, Basic 1 (IHD) : OE14)(Oral Presentation (English))
• Rho Activation and Extracellular Signal-Regulated Kinase (ERK) Downregulation Are Crucial for eNOS Downregulation in Monocyte Adhesion to Endothelial Cells
• Thrombin-lnduced Downregulation of Endothelial Nitric Oxide Synthase (eNOS) via Rho Activation in Human Endothelial Cells :Involvement of Geranylgeranyl Transferase Activation
• Thrombin-Stimulated Ca^ Signaling Mediated via RhoA Activationin Tissue Factor (TF) and Plasminogen Activator Inhibitor-1 (PAI-1) Synthesis in Endothelial Cells
• RhoA Activation Plays an Integral Role in Tissue Factor (TF) Gene Expression
• Oxidized LDL Downregulates Endothelial Nitric Oxide Synthase (eNOS) via Rapid RhoA Activaion in Endothelial Cells
• OE-073 Quantitative Analysis of Change in Early Diastolic Strain Rate for Adenosine-Induced Myocardial Dysfunction(OE13,Echo/Doppler (New Technology) (I),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PE-322 SPECT/CTCA Fusion Image is Useful for the Diagnosis of Coronary Artery Stenosis with Calcification(PE054,CT/MRI (New Technology) (I),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• DPJ-024 Serum NT-proBNP Level for Diagnosis of Diastolic Heart Failure in Japanese Population(DPJ04,Heart Failure (Diagnosis) (M),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-027 Adaptive Servo Ventilation Improves Cardiac Function in Heart Failure Patients with Cheyne-Stokes Respiration(OE05,Obesity/SAS (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
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• OJ-039 Correlation between Atherosclerotic Plaque Instability and Matrix Metalloproteinase(MMPs) Expression in Autopsy Cases of Diabetes Mellitus(DM)(Diabetes/Obesity 1 (H) : OJ5)(Oral Presentation (Japanese))
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