OJ-420 Protective effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by repeated epicardial endothelial injury.(Endothelium/NO 5 (H) : OJ51)(Oral Presentation (Japanese))

スポンサーリンク

概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2004-03-01

著者

• Saitoh Shuichi

  First department of internal medicine, Fukushima Medical University

• Ishibashi Toshiyuki

  First department of internal medicine, Fukushima Medical University

• Ishibashi Toshiyuki

  First Department Of Internal Medicine Fukushima Medical University

• Maruyama Yukio

  Department Of Cardiology And Hematology Fukushima Medical University

• Matsumoto Ken

  First Department of Internal Medicine, Fukushima Medical University

• Ohsugi Taku

  First Department of Internal Medicine, Fukushima Medical University

• Maruyama Yukio

  First Department Of Internal Medicine Fukushima Medical University

• Osugi Taku

  First Department Of Internal Medicine Fukushima Medical University

• Ohsugi Taku

  First Department Of Internal Medicine Fukushima Medical University

• Maruyama Yukio

  First Department Of Internal Medicine Fukushima Medical College

• Saitoh Shuichi

  First Department Of Internal Medicine Fukushima Medical University

• Matsumoto Ken

  First Department Of Internal Medicine Fukushima Medical University

• Saitoh Shuich

  First Department Of Internal Medicine Fukushima Medical University

• Muto Mitsuru

  First Department of Internal Medicine, Fukushima Medical University

• Aikawa Kazuhiko

  First Department of Internal Medicine, Fukushima Medical University

• Muto Mitsuru

  First Department Of Internel Medicine Fukushima University Of Medicine

• Muto Mitsuru

  First Department Of Internal Medicine Fukushima Medical University

• Aikawa Kazuhiko

  First Department Of Internel Medicine Fukushima University Of Medicine

• Saitoh Shuichi

  The First Department Of Internal Medicine Fukushima Medical University

• Ishibashi Toshiyuki

  First Department Of Fumusima Medical University

関連論文

• PJ-127 Initial Result of Retrograde Approach for Chronic Total Occlusion (CTO) Lesions of Coronary Artery Disease(PJ021,Coronary Revascularization, PCI (Complex Lesions) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Ci
• PJ-127 Initial Result of Retrograde Approach for Chronic Total Occlusion (CTO) Lesions of Coronary Artery Disease(PJ021,Coronary Revascularization, PCI (Complex Lesions) (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Ci
• 38)マクロファージにおけるヘムオキシゲナーゼ1由来の一酸化炭素による活性酸素種発生の抑制(第144回日本循環器学会東北地方会)
• 44) 抗不整脈薬投与で徐伯化してしまい治療に難渋した持続性心室頻拍の一例(第145回日本循環器学会東北地方会)
• 診断・治療ガイドラインの概要 急性心不全治療ガイドライン (大規模臨床試験--循環・代謝系を中心に) -- (心不全)
• 14) ICD植え込み後に自家末梢血幹細胞移植を施行し,心筋拡張障害の改善を確認し得た心アミロイドーシスの一例(第145回日本循環器学会東北地方会)
• Participation of mast cells in angiogenesis in the border zone of myocardial infarction in rats
• OE-296 Metabolic Regulation of Coronary Vascular Tone : Role of Hydrogen Peroxide, Adenosine 5'-diphosphate, and Angiotensin(OE50,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (English),The 73rd Annual Scientific M
• Attenuation of Cardioprotective Effect by Postconditioning in Coronary Stenosed Rat Heart and Its Restoration by Carvedilol
• 高脂血症患者における短期の脂質低下は心筋内微小循環障害を改善する : 心筋コントラストエコー法による評価
• PJ-294 Quantitative Analysis of Change in Early Diastolic Strain Rate for Exercise Induced Myocardial Ischemia: Comparison with TC^ Myocardial Scintigraphy(Echo/Doppler(14)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
• PJ-059 Single Sirolimus-Eluting Stent Implantation after Directional Coronary Atherectomy for Left Main Bifurcation Lesions(Coronary revascularization, PCI(16)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation So
• PE-533 Short-term Cholesterol-lowering Therapy Improves Myocardial Microvascular Dysfunction in Patients with Hypercholesterolemia : Evaluation of Myocardial Blood Velocity by Myocardial Contrast Echocardiography(Echo/Doppler(10)(I),Poster Session(English
• PE-388 Atorvastatin Blocks an Advanced Glycation End Products (AGE) : Receptor for AGE(RAGE) Axis in Diabeteic Vascular Responses(Cardiovascular pharmacology, basic/clinical(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese
• PE-086 New Insights into Oxidized LDL-induced RhoA and Rac1 Activation by an LOX-1-MT1-MMP Axis in Endothelial Dysfunction(Endothelium(02)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-248 New Developed Powerful Tool for Detecting of Exercise Induced Myocardial Dysfunction : Assessment of Early Diastolic Strain Rate(Echo / Doppler(04)(I),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
• Attenuation of Diastolic Heart Failure and Life-Threatening Ventricular Tachyarrhythmia After Peripheral Blood Stem Cell Transplantation Combined With Cardioverter-Defibrillator Implantation in Myeloma-Associated Cardiac Amyloidosis
• Prediction of Remote Left Ventricular Volumes and Functions After Acute Myocardial Infarction With Successful Coronary Intervention
• Radial strain rate のカラーマッピングによる運動負荷誘発性心筋虚血の同定 : Tc^心筋シンチとの比較
• Influences of Autonomic Nervous System on Atrial Arrhythmogenic Substrates and the Incidence of Atrial Fibrillation in Diabetic Heart
• DPJ-072 Regulation of Coronary Vascular Tone via Redox Modulation in the Alpha1-Adrenergic-Angiotensin-Endothelin Axis of the Myocardium(DPJ12,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Digital Poster Session (Japanese),The 73rd
• RhoA and Rac1 Changes in the Atherosclerotic Lesions of WHHLMI Rabbits
• PE-493 Rapid Improvement of Impaired Endothelium-Dependent Vasodilation and Rac1/NADPH Oxidase-Derived ROS Generation in Vivo by Pravastatin(PE083,Cardiovascular Pharmacology (Basic), Cost-health Care System/DPC/Laws (H),Poster Session (English),The 73rd
• OE-091 Involvement of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) in Advanced Glycation End Products (AGE)/RAGE-Signaling Pathways(OE16,Diabetes (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-664 LOX-1 plays a crucial role in RhoA-and Rac1-dependent signaling through Gi induced by oxidized low-density lipoprotein in endothelial cells(Molecular biology, vascular-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-559 Pravastatin Rapidly Prevents Thrombin-induced Vasoconstriction and NADPH Oxidase-dependent ROS Generation in vivo : Implications for Beneficial Effect(Cardiovascular pharmacology, basic/clinical-5, The 71st Annual Scientific Meeting of the Japanese
• PJ-216 Receptor for Advanced Glycation End Products (RAGE) Plays a Crucial Role in Atherosclerosis(Atherosclerosis, basic-9, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-067 New Insights into Regulation of Diabetic Vascular Remodeling by an MT1-MMP-RAGE axis(Atherosclerosis, basic-8, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-197 RhoA-Dependent PAI-1 Gene Exprssion Induced in Endothelial Cells by Monocyte Adhesion is Mediated Via Geranylgeranyl Transferase I and Ca^ Signaling(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Societ
• PJ-475 Crucial Role of Geranylgeranyl Transferase I in AGE-Induced Gene Expression in Diabetes(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-473 A Novel Role of LOX-1 in Monocyte Adhesion-Induced Gene Expression via Redox-Sensitive and Ca^ Signaling Pathways in Endothelial Cells(Atherosclerosis, basic-5 (H) PJ80,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of
• PJ-102 MT1-MMP-RAGE Axis in Regulation of Advanced Glycation End Products (AGEs)-Dependent Redox-sensitive Signaling(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulatio
• PE-003 Increased Expression of Matrix Metalloproteinase-9 and Apoptosis Induced by Advanced Glycation Endproducts in Type 2 Diabetes : Implications for Plaque Instability(Acute coronary syndrome, basic/clinical-4 (IHD) PE1,Poster Session (English),The 70t
• OJ-262 A Role of Reactive Oxygen Species in Coronary Spasm(Coronary circulation, basic/clinical-2 (IHD) OJ44,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-164 Essential Role of Rapid Geranylgeranylation from Unprocessed RhoA in RhoA Activation and Increase in Unprocessed RhoA in Atherosclerosis(Endothelium-2 (H) OJ28,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japan
• Monocyte Adhesion to Endothelial Cells Activates p47phox/NF-kB via Renin-Angiotensin System(RAS), Resulting in Gene Induction of MCP-1, ICAM-1 and Tissue Factor (Atherosclerosis, Basic 9 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulatio
• Activation of CCR2 by MCP-1 Accelerates TF Expression via Ca2+ Influx in Monocyte Adhesion to Nitric Oxide (NO)-Impaired Endothelial Cells(Atherosclerosis, Basic 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Blockade of Renin-angiotensin System (RAS) Inhibits Oxidized LDL-induced Superoxide Generation by Suppressing NADPH Oxidase Component Nox-4, p47 phox and Rac(Atherosclerosis, Basic 8 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation So
• Membrane type 1 Metalloproteinase (MT1-MMP) is Involved in the RhoA-dependent eNOS Downergulation Induced by Oxidized LDL in Endothelial Cells(Atherosclerosis, Basic 4 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PE-538 Human Autologous Bone Marrow-derived Cell Transplantation(BMCT) Combined with Off-pump Coronary Bypass Surgery(OPCAB), Assessment of Feasibility, Mechanisms and Histopathological Findings(Regeneration (angionenesis/myocardial regeneration)-4 (M) PE
• Difference in Early Effects of Statin Therapy on Coronary and Forearm Flow Reserve in Postmenopausal Hypercholesterolemic Women
• PJ-250 Difference in Short-term Effects of Statin Therapy on Coronary and Forearm Flow Reserve in Postmenopausal Hypercholesterolemic Japanese Women(Echo/Doppler-16, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-170 Assessment of Microvascular Dysfunction by Myocardial Blood Velocity in Patients with Hyperlipoproteinemia(Echo / Doppler-06, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-275 Improvement of Microvascural Dysfunction by Cholesterol-lowering Therapy in Patients with Hypercholesterolemia is Different between Forearm and Coronary Arterial Beds(Echo/Doppler-5 (I) OJ46,Oral Presentation (Japanese),The 70th Anniversary Annual
• Role of Ca^ Influx in Tissue Factor Expression in Monocyte Adhesion to Endothelial Cells
• Inhibition of Matrix Metalloproteases (MMPs) Suppresses Rac/NADPH Oxidase-derived Reactive Oxygen Species (ROS) Generation in Oxidized Low Density Lipoprotein-stimuleted Endothelial Cells(Atherosclerosis, Basic 4 (IHD), The 69th Annual Scientific Meeting
• Therapeutic Effect of Intravenous Administration of Statin on eNOS Downregulation and ROS Generation in Response to Thrombin in Vivo(Cardiovascular Pharmacology, Basic/Clinical 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-582 Intravenous administration of statin prevents RhoA activation-triggered eNOS downregulation and reactive oxygen species induced by thrombin in rats(Cardiovascular Pharmacology, Basic/Clinical 5 (H) : PJ98)(Poster Session (Japanese))
• PE-216 Mechanism and Role of Geranylgeranylation in RhoA Activation in Endothelial Dysfunction(Metabolism/Biochemistry/Energetics 1 (IHD) : PE37)(Poster Session (English))
• OE-118 Inhibition of Matrix Metalloproteinases (MMPs) Suppresses the RhoA-dependent eNOS Downergulation Induced by Oxidized LDL in Endothelial Cells(Atherosclerosis, Basic 1 (IHD) : OE14)(Oral Presentation (English))
• Rho Activation and Extracellular Signal-Regulated Kinase (ERK) Downregulation Are Crucial for eNOS Downregulation in Monocyte Adhesion to Endothelial Cells
• Thrombin-lnduced Downregulation of Endothelial Nitric Oxide Synthase (eNOS) via Rho Activation in Human Endothelial Cells :Involvement of Geranylgeranyl Transferase Activation
• Thrombin-Stimulated Ca^ Signaling Mediated via RhoA Activationin Tissue Factor (TF) and Plasminogen Activator Inhibitor-1 (PAI-1) Synthesis in Endothelial Cells
• RhoA Activation Plays an Integral Role in Tissue Factor (TF) Gene Expression
• Oxidized LDL Downregulates Endothelial Nitric Oxide Synthase (eNOS) via Rapid RhoA Activaion in Endothelial Cells
• PE-322 SPECT/CTCA Fusion Image is Useful for the Diagnosis of Coronary Artery Stenosis with Calcification(PE054,CT/MRI (New Technology) (I),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• DPJ-024 Serum NT-proBNP Level for Diagnosis of Diastolic Heart Failure in Japanese Population(DPJ04,Heart Failure (Diagnosis) (M),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-027 Adaptive Servo Ventilation Improves Cardiac Function in Heart Failure Patients with Cheyne-Stokes Respiration(OE05,Obesity/SAS (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Role of Advanced Glycation End Products (AGEs) in Increased Matrix Metalloproteinases (MMPs) Expression in Patients with Diabetes Mellitus (DM)(Diabetes/Obesity 9 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-039 Correlation between Atherosclerotic Plaque Instability and Matrix Metalloproteinase(MMPs) Expression in Autopsy Cases of Diabetes Mellitus(DM)(Diabetes/Obesity 1 (H) : OJ5)(Oral Presentation (Japanese))
• PJ-833 Assessment of Left Atrial Function : Comparison of MDCT and Echocardiography(CT / DSA(11)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-252 Metabolic Regulation of Coronary Vascular Tone : Role of Hydrogen Peroxide, Purinergic Component, and Angiotensin.(Coronary circulation, basic/clinical(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation
• PJ-248 Regulation of Coronary Vascular Tone via Redox Modulation in the Alpha-Adrenergic-Angiotensin-Endothelin Axis of the Myocardium(Coronary circulation, basic/clinical(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanes
• PE-067 Comparative Analysis of the Incidence of Metabolic Syndrome among Different Age Groups in the Patients with Coronary Artery Disease(Diabetes/Obesity/Metabolic syndrome(04)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanes
• PJ-217 Monocyte Adhesion Induces Gene Expression Mediated via LOX-1-dependent Signaling Pathways in Endothelial Cells(Atherosclerosis, basic-9, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Expression of Cytokine and Adhesion Molecule mRNA in Atherectomy Specimens From Patients With Coronary Artery Disease
• IS112 Granulocyte-macrophage colony-stimulating factor alters cellular and extracellular composition of atherosclerotic lesions and reduces atherosclerosis in atherogenic rabbits
• OE-031 Characteristics of Hospitalized Heart Failure Patients Who Have Also Chronic Kidney Disease(Heart failure, clinical-01, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Very low density lipoprotein receptor mRNA in monocytes is upregulated by hypoxia
• PJ-583 Pravastatin Inhibits the Generation of Reactive Oxygen Species Induced byThrombin in Endothelial Cells and Cardiomyocytes(Cardiovascular Pharmacology, Basic/Clinical 5 (H) : PJ98)(Poster Session (Japanese))
• OJ-217 Role of geranylgeranyl transferase activation and Ca^ Signaling in Plasminogen Activator Inhibitor-1 Expression in Endothelial Cells Triggered by Monocyte Adhesion(Blood Coagulation/Fibrinolysis (IHD) : OJ24)(Oral Presentation (Japanese))
• OJ-049 Nicorandil Suppresses Thrombin-induced Tissue Factor (TF) and Plasminogen Activator Inhibitor-1 Expression (PAI-1) via Blockade of Ca^ influx in Endothelial Cells(Antithrombofic Ttherapy (H) : OJ6)(Oral Presentation (Japanese))
• OE-274 HMG-CoA Reductase Inhibitor (Statin) Possibly Functions as Ca^ Antagonist in Endothelial Cells(Cardiovascular Pharmacology, Basic/Clinical 1 (H) : OE34)(Oral Presentation (English))
• Blockade of Renin-Angiotensin System Downregulates TF in Monocyte Adhesion to Endothelial Cells via Suppressing ICAM-1, MCP-1 Expression and Ca^ Signaling
• Role of Hydrogen Peroxide (H_2O_2) on Non Selective Cation Current on Endothelial Cells Stimulated by Lysophosphatidylcholine (LPC)
• HMG-CoA Reductase Inhibitors (Statins) Suppress Nonselective Cation Current Induced by Lysophosphatidylcholine in Endothelial Cells
• Inhibition of Rho/Rho-kinase signaling rescues the downregulated eNOS synthesis induced by thrombin in endothelial cells
• Thrombin-stimulated Ca^ mobilization mediated via Gi through Rho/Rho-kinase is involved in tissue factor (TF) synthesis in endothelial cells (ECs)
• Comprehensive Analyses of Arrhythmogenic Substrates and Vulnerability to Ventricular Tachycardia in Left Ventricular Hypertrophy in Salt-Sensitive Hypertensive Rats
• FRS-054 Continuous Decrease of Parasympathetic and Sympathetic Nervous Activities before Increased Sympathetic Nervous Activities Is Prerequisite to The Induction of Coronaryspasm(Oxidative Stress, Autonomic Function and Peripheral Vascular Diseases (H) :
• Endothelin A Antagonist Prevents the Development of Microvascular Spasm Induced by Repeated Endothelial Injury of Epicardial Coronary Artery
• Different Contribution of Apoptosis to the Antiproliferative Effects of L-Arginine, Enalapril and Losartan on Neointimal Growth Inhibition After Balloon Arterial Injury
• Antioxidants prevent coronary microvascular dysfunction induced by repeated epicardial coronary artery endothelial denudation in pigs
• PJ-009 Endothelin Type A Receptor Antagonist Has a Protective Effect on Coronary Microvascular Spasm Induced by Repeated Epicardial Endothelial Injury(Coronary circulation, basic/clinical-4 (IHD) PJ2,Poster Session (Japanese),The 70th Anniversary Annual S
• PJ-227 Different anti-ischemic heart failure effect of L-arginine or tetrahydrobiopterin and nitrate through their effects on ischemia-induced oxidative stress generation(Heart Failure, Basic 2 (M) : PJ38)(Poster Session (Japanese))
• OJ-420 Protective effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by repeated epicardial endothelial injury.(Endothelium/NO 5 (H) : OJ51)(Oral Presentation (Japanese))
• FRS-068 Chronic endothelin type A receptor antagonist has a protective effect on coronary spasm induced by repeated epicardial endothelial injury.(Atherosclerosis (IHD) : FRS8)(Featured Research Session (English))
• PJ-460 Metabolic Regulation of Coronary Vascular Tone through Redox Modulation(Coronary circulation, basic/clinical-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• THE INHIBITORY EFFECT OF ENALAPRIL ON THE NEOINTIMAL FORMATION AFTER ARTERIAL INTIMAL INJURY VIA APOPTOSIS
• Multiple endothelial injury in epicardial coronary artery induces downstream microvascular spasm through oxygen free radical and endothelin-1
• Antioxidant therapy prevents coronary artery spasm in pig
• Blockade of Endothelin-1 Prevents Coronary Spasm Induced by repeated Epicardial Endothelial Injury in a Pig Model (Endothelium/NO 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Chronic Endothelin Type A Antagonist is Effective to Prevent Coronary Microvascular Spasm Induced by Repeated Endothelial Injury(Coronary Circulation, Basic/Clinical 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Effects of β-Blockers on Coronary Spasm Induced by Repeated Epicardial Coronary Artery Endothelial Denudation in Pigs
• Effects of Granulocyte-Macrophage Colony-Stimulating Factor on the Levels of VLDL and LDL Receptor mRNAs in vivo
• 0688 DEVELOPMENT OF PIG CORONARY MICROVASCULAR SPASM MODEL AND RELATION OF NITRIC OXIDE
• ALTERATION OF RESPONSES TO VASOACTIVE AGENTS IN THE PROCESS OF REPEATED ENDOTHELIAL. INJURY AND REGENERATION IN A PIG CORONARY ARTERY
• Specificity of Vascular Reactivity and Remodeling After Repeated Endothelial Injury in a Swine Model
• Blockade of renin-angiotensin system downregulates tissue factor induced by monocyte-adhesion to endothelial cells via suppressing ICAM-1 and Ca^ signaling
• Inhibition of Rho and Rho-kinase downregulates the synthesis of tissue factor and plasminogen activator inhibitor-1 in cultured human monocytes

もっと見る 閉じる

スポンサーリンク