RELATIONSHIP OF THALLIUM-201 DEFECT AND LEFT VENTRICULAR FUNCTION AFTER DIPYRIDAMOLE INFUSION

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概要

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• T1-201 imaging and first-pass radionuclide ventriculography (RNV) by 4 min infusion of 0.56 mg/kg dipyridamole were performed on 22 patients with coronary artery disease in order to know the relationship of myocardial perfusion and left ventricular function after dipyridamole-infusion, and thereby to define whether T1-201 images were divided into anterior, apical, and infero-posterior segments, and segmental perfusion defects were categorized as reversible, fixed and no defect. RNV on the 30-degree right anterior oblique view was also divided into anterior, apical, and infero-posterior wall to be evaluated for regional wall motion by a 5 point score before and after dipyridamole. Changes in left ventricular ejection fraction (LVEF) with dipyridamole were also calculated. Normal responses of regional wall motion and LVEF to dipyridamole were established from the data of 14 normal subjects. Reversible defects were closely associated (69%) with an abnormal response of regional wall motion (score decrease of 1 or more after dipyridamole). Both fixed defects and no defects showed little association with abnormal response of regional wall motion. Moreover, 77% of the patients having reversible-defect segment showed an abnormal response of LVEF (reduction of 3% or more following dipyridamole). However, patients without reversible defect did not show and abnormal response to dipyridamole. These results suggest that dipyridamole-induced T1-201 defects represent a myocardial ischemia which causes a reduction of ventricular function.

• 社団法人日本循環器学会の論文
• 1989-07-20

著者

• Takeishi Yasuchika

  First department of internal medicine, Fukushima Medical University

• Tsuiki Kai

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Takeishi Yasuchika

  First Department Of Internal Medicine Fukushima Medical University

• Takeishi Yasuchika

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Kanaya Tohru

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Kanaya Toru

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Tsuiki Kai

  First Dept. Of Inter. Med Tohoku Univ. School Of Med.

• Yasui S

  The Department Of Public Health

• TONOOKA ICHIRO

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• MEGURO MITSUHIKO

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• MASAKANE IKUTO

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• YAMAGICHI YOSHIKO

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• HOSHI HIKARU

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• KANAYA TOHRU

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• KOMATANI AKIO

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• YASUI SHOJI

  First Department of Internal Medicine and Department of Radiology, Yamagata University School of Med

• Tonooka Ichiro

  The First Department of Internal Medicine, Yamagata University School of Medicine

• Meguro Mitsuhiko

  The First Department of Internal Medicine Yamagata University School of Medicine

• Masakane Ikuto

  The First Department of Internal Medicine, Yamagata University School of Medicine

• Yamaguchi Seiji

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Kanaya Tohru

  First Department Of Internal Medicine And Department Of Radiology Yamagata University School Of Medi

• Tuiki Kai

  The 1st Dept. of Yamagata University

• Komatani Akio

  First Department Of Internal Medicine And Department Of Radiology Yamagata University School Of Medi

• Tonooka Ichiro

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Hoshi Hikaru

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Konta Tsuyoshi

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Masakane Ikuto

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Yasui Shoji

  First Deparment Of Internal Medicine Nagoya University School Of Medicine

• Tono-oka Ichiro

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• Tsuiki Kai

  The 1st Department Of Internal Medicine Yamagata University School Of Medicine

• Kanaya Tohru

  First Department Of Internal Medicine And Department Of Radiology Yamagata University School Of Medi

• Yamagichi Yoshiko

  The First Department Of Internal Medicine Yamagata University

• Takahashi Keiji

  The First Department Of Internal Medicine Yamagata University School Of Medicine

• TSUIKI Kai

  First Department of Internal Medicine, Tohoku University School of Medicine

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