Hypersomnia Caused by Isolated Angiitis of the CNS
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概要
- 論文の詳細を見る
A 42-year-old woman presented gradual development of hypersomnia and memory disturbance. T2-weighted and FLAIR MRI scans revealed a high intensity abnormality in the hypothalamus. Stereotactic brain biopsy specimen revealed prominent infiltration of the lymphocytes in the vessel walls. Since there was no evidence of systemic angiitis, the diagnosis of isolated angiitis of the CNS (IAC) was made. Polysomnographic study showed decreased REM sleep and increased stage I sleep. Orexin A in the CSF was decreased. Hypersomnia and a decrease of the CNS orexin A improved after corticosteroid therapy. Hypersomnia can be an initial symptom of IAC if it involves the hypothalamus.
著者
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IKEDA Akio
Departments of Neurology, Kyoto University Graduate School of Medicine
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SHIBASAKI Hiroshi
Department of Neurology, Kyoto University Graduate School of Medicine
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TOMIMOTO Hidekazu
Department of Neurology, Kyoto University School of Medicine
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Shimohama Shun
Department of Neurology, Sapporo Medical University School of Medicine
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Ikeda Akio
Departments Of Neurology Kyoto University Graduate School Of Medicine
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Shimohama Shun
Department Of Neurology Faculty Of Medicine Kyoto University
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OKA YASUNORI
Department of Neuropsychiatry, Ehime University School of Medicine
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Tomimoto Hidekazu
Department Of Neurology Faculty Of Medicine Kyoto University
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Shibasaki Hiroshi
Department Of Brain Pathophysiology Human Brain Research Center Kyoto University School Of Medicine
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Oka Yasunori
Department Of Neuropsychiatry Ehime University School Of Medicine
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KANBAYASHI TAKASHI
Department of Psychiatry, Akita University School of Medicine
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NAKAJI Kayoko
Department of Neurology, Kyoto University Graduate School of Medicine
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Kanbayashi Takashi
Department Of Neuropsychiatry Akita University Graduate School Of Medicine
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Ikeda Akio
Department Of Applied Chemistry & Biotechnology Faculty Of Engineering Yamanashi University
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TOMIMOTO Hidekazu
Department of Neurology, Kyoto University Graduate School of Medicine
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SHIMOHAMA Shun
Department of Neurology, Kyoto University Graduate School of Medicine
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OKA Yasunori
Department of Neurology, Kyoto University Graduate School of Medicine
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