CSF HYPOCRETIN CONCENTRATION IN VARIOUS NEUROLOGICAL AND SLEEP DISORDERS
スポンサーリンク
概要
- 論文の詳細を見る
Recent CSF and postmortem brain hypocretin measurements in human narcolepsy suggest that hypocretin deficiency is involved in the pathophysiology of the disease. Thus, it is important to study whether neurological disorders also have abnormal CSF hypocretin levels. We therefore measured hypocretins in the CSF of various neurological disorders and obstructive sleep apnea syndrome (OSAS) to identify altered hypocretin levels. CSF hypocretin levels in patients with OSAS and neurological diseases were almost within the normal range in Japanese populations. While, hypocretin levels in patients with narcolepsy-cataplexy are very low. The measurement of hypocretin levels is a useful diagnostic tool in Japanese patients with narcolepsycataplexy.
著者
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KANBAYASHI TAKASHI
Department of Psychiatry, Akita University School of Medicine
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Tsutsui Kou
Department Of Psychiatry Akita University School Of Medicine
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Sato Masahiro
Department Of Child Neourology Okayama University Medical School
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Shimizu Tetsuo
Department Of Neuropsychiatry Akita University School Of Medicine
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Shimizu Tetsuo
Department Of Neuropsychiatry Akita University Hospital
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Sawaishi Yukio
Akita Prefectural Center On Development And Disability
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Tokunaga Jun
Department of Neuropsychiatry, Akita University Graduate School of Medicine
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Shimizu Tetsuo
Department Of Neuropsychiatry Akita University Graduate School Of Medicine
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Kanbayashi Takashi
Department Of Neuropsychiatry Akita University Graduate School Of Medicine
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Tokunaga Jun
Department Of Neuropsychiatry Akita University Graduate School Of Medicine
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Sato Masahiro
Department Of Neuropsychiatry Akita University Graduate School Of Medicine
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Sato Masahiro
Department Of Agricultural Chemistry The University Of Tokyo:(present Office)k. I. Chemical Research
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Shimizu Tetsuo
Department Of Electrical Engineering Nagaoka University Of Technology
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Tsutsui Kou
Department Of Neuropsychiatry Akita University Graduate School Of Medicine
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SHIMIZU Tetsuo
Department of Civil Engineering The University of Tokyo
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