Transient Increase in Epileptiform Discharges after the Introduction of Nasal Continuous Positive Airway Pressure in a Patient with Obstructive Sleep Apnea and Epilepsy
スポンサーリンク
概要
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In patients with obstructive sleep apnea (OSA) and epilepsy, the frequency of generalized spike and wave complexes (GSWCs) usually decreases after the initiation of nasal continuous positive airway pressure (nCPAP) therapy. However, we herein report a patient who had a transient increase in GSWCs following nCPAP treatment. A woman with epilepsy underwent polysomnography, who showed severe OSA and 30 GSWCs during the sleep study. Polysomnography at the introduction nCPAP showed that the GSWCs increased to 94 times during the monitoring period, despite improvement of her OSA. Polysomnography was again performed four months later, and the GSWCs had decreased to 23 times. Physicians should therefore be cautious regarding a possible increase in epileptiform discharges and seizures immediately after the introduction of nCPAP.
著者
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Oga Toru
Department Of Pharmacology Kyoto University Faculty Of Medicine
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Chin Kazuo
Department Of Physical Therapeutics Kyoto University
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Hitomi Takefumi
Department Of Neurology Kyoto University Graduate School Of Medicine
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Takahashi Ryosuke
Department Of Natural History Sciences Graduate School Of Science Hokkaido University
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Ikeda Akio
Department Of Applied Chemistry & Biotechnology Faculty Of Engineering Yamanashi University
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KATO Takeo
Department of Applied Physics, Osaka City University
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Tsuboi Tomomasa
Department of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University, Japan
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Tsuboi Tomomasa
Department of Rehabilitation Medicine, Kyoto University Hospital
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Yoshimura Chikara
Department of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University, Japan
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Kato Takeo
Department of Pediatrics, Graduate School of Medicine, Kyoto University, Japan
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Hitomi Takefumi
Department of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto University, Japan
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