CHARACTERIZATION OF TRANSPLANTABLE SUBLINE MDCC-MSB1-CLO. 18 DERIVED FROM MDCC-MSB1

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概要

• 論文の詳細を見る

• MDCC-MSB1-Clo. 18 subline, derived from a Marek's disease (MD) lymphoblastoid cell line MDCC-MSB1,was highly transplantable and lethal for chickens. A dose-response relationship was observed between the number of tumor cells inoculated and the development of tumors in the recipient chickens. In addition to lymphoma formation at the site of transplantation, the recipients developed metastatic lesions in various visceral organs. Age resistance of the chickens to the tumor development was also observed. No tumor development was observed in nude mice inoculated with MDCC-MSB1-Clo. 18 cells. MD virus was isolated from duck embryo fibroblasts inoculated with MDCC-MSB1-Clo. 18 cells and also from kidney cell cultures of MDCC-MSB1-Clo. 18-inoculated chickens. MDCC-MSB1-Clo. 18 cells reacted with anti-B_E and B_K sera in the membrane immunofluorescence test. The tumor cells collected from the chickens also reacted with anti-B_E and B_K sera, while the erythrocytes from these chickens did not react with these antisera. This indicated that the tumors were originated from the inoculated cells.

• 北海道大学の論文
• 1984-07-25

著者

• Mikami Takeshi

  Department Of Veterinary Microbiology Faculty Of Agriculture The University Of Tokyo

• KODAMA Hiroshi

  Department of Veterinary Immunology, College of Agriculture, University of Osaka Prefecture

• IZAWA Hisao

  Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University

• HIGASHIHARA Tomoko

  Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University

• KUNIHIRO Kazuaki

  Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University

• YAMAKI Tetsuya

  Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University

• OKADA Ikuo

  Department of Animal Science, Faculty of Applied Biological Science, Hiroshima University

• Kodama H

  Osaka Prefecture Univ. Osaka Jpn

• Okada Ikuo

  Department Of Animal Science Faculty Of Applied Biological Science Hiroshima University

• Okada Ikuo

  Department Of Animal Husbandry Faculty Of Agriculture Hokkaido Unviersity

• Yamaki Tetsuya

  Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University

• MOKUDAI Toshie

  Gunma Prefectural Meat Inspection Laboratory

• Mikami T

  Gunma Prefectural Meat Inspection Laboratory

• Mikami Takeshi

  Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University

• Kunihiro Kazuaki

  Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University

• Higashihara Tomoko

  Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University

• Izawa Hisao

  Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University

• Kodama Hiroshi

  Department Of Veterinary Immunology College Of Agriculture University Of Osaka Prefecture

• 児玉 洋

  Osaka Prefecture Univ. Osaka Jpn

• Kodama Hiroshi

  Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University

• Mikami Takeshi

  Laboratories Of Veterinary Public Health Department Of Veterinary Medicine College Of Bioresource Sc

• MIKAMI Takeshi

  Department of Cardiovasology, Surugadai Nihon University Hospital

• OKADA Ikuo

  Department of Animai Science, Faculty of Agriculture, Hokkaido University

• Kodama Hiroshi

  Department of Chemistry, Faculty of Science, Hokkaido University

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