Change in the Respiration System of Candida albicans in the Lag and Log Growth Phase(Microbiology)
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概要
- 論文の詳細を見る
The growth rate of Candida albicans at the lag growth phase was not influenced by sodium sulfite, but that at the log growth phase was remarkably inhibited. C. albicans was able to grow in aerobic conditions both with and without glucose. Under anaerobic conditions, the growth of C. albicans was completely inhibited in glucose-free RPMI1640 medium. Ethanol production was increased at the lag growth phase, but decreased at the log growth phase. When oligomycin was added to the aerobic growth condition, the growth at log growth phase was remarkably inhibited. The expression of SDH2 mRNA was low in the lag growth phase and high in the log growth phase. We concluded that C. albicans obtained ATP by fermentation at the lag growth phase, and needed oxygen to generate ATP by oxidative phosphorylation at the log growth phase.
- 公益社団法人日本薬学会の論文
- 2006-03-01
著者
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Mikami Takeshi
Department Of Veterinary Microbiology Faculty Of Agriculture The University Of Tokyo
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Mikami T
Department Of Microbiology Tohoku Pharmceutical University
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Mikami Takeshi
東北薬科大学 微生物学
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渡部 俊彦
東北薬大
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Ogasawara Ayako
Department Of Microbiology Tohoku Pharmceutical University
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WATANABE TOSHIHIKO
Department of Surgery, Tachikawa Kyosai Hospital
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Watanabe T
Department Of Clinical Biochemistry Faculty Of Pharmaceutical Science Tokyo University Of Pharmacy A
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Watanabe T
Dept. Clin. Biochem. Sch. Pharm. Sci. Tokyo College Of Pharmacy
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Watanabe T
Department Of Clinical Biochemistry Tokyo College Of Pharmacy:laboratory Of Molecular Biology Azabu
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Mikami Takeshi
Department Of Epizootiology Faculty Of Veterinary Medicine Hokkaido University
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MATSUMOTO Tatsuji
Department of Microbiology, Tohoku Pharmacentical University
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ODAHARA Kyoko
Department of Microbiology, Tohoku Pharmaceutical University
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TOUME Mikiko
Department of Microbiology, Tohoku Pharmaceutical University
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MURAKAMI Tomonori
Department of Microbiology Tohoku College of Pharmacy
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Matsumoto T
Department Of Microbiology Tohoku Pharmceutical University
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Odahara Kyoko
Department Of Microbiology Tohoku Pharmaceutical University
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Watanabe Takafumi
Department Of Clinical Biochemistry Tokyo College Of Pharmacy:laboratory Of Molecular Biology Azabu
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Watanabe T
School Of Pharmacy Tokyo University Of Pharmacy And Life Science
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Ogasawara Ayako
Department Of Microbiology Tohoku Pharmaceutical University
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松本 達二
東北薬大
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Watanabe Takafumi
Department Of Clinical Biochemistry Tokyo College Of Pharmacy:laboratory Of Molecular Biology Azabu
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Watanabe Toshihiko
Department Of Aeronautics And Astronautics University Of Tokyo
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Ogasawara Ayako
Department of Microbiology, Tohoku Pharmaceutical University
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松本 達二
Department of Microbiology, Tohoku Pharmaceutical University
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MIKAMI Takeshi
Department of Cardiovasology, Surugadai Nihon University Hospital
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