西太平洋地区4カ国(日本,中国,韓国,ベトナム)の薬局方収載生薬の各種試験法並びに規格値の比較に関する研究(第4報) : クリーンアナリシスと国際調和を指向したTLC条件の比較

概要

論文の詳細を見る
Recently, from the viewpoint of prevention of environmental pollution and the health protection of researcher, clean analysis removing harmful chemical reagents such as benzene and chloroform is recommended worldwide. At the fourth Western Pacific Regional Forum for the Harmonization of Herbal Medicines (FHH) Standing Committee in Tokyo 2006, we proposed the collaborative study of the developing solvent for TLC identification in Pharmacopoeia, considering clean analysis. The proposed collaboration study is as follows: each member state tests the TLC analysis using non-toxic solvent systems which are described in other members' Pharmacopoeia with regard to the designgted crude drugs in the comparative table. In this paper, we show the results of the task work. From our comparative study, it is suggested that for almost all TLC identification of crude drugs using chloroform (or benzene) as a developing solvent, non-toxic solvent systems will be able to replace the toxic solvents.
日本生薬学会の論文
2008-08-20