中華人民共和国葯典2005年版に収載された体外培育牛黄の特徴

概要

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In China, CBS has been used as an alternative to BEZOAR BOVIS (BB). CBS consists of several ingredients derived from BB and is made ex vivo. This experiment has been carried out to enable the discrimination between CBS and BB. Comparison with BB revealed the following characteristics of CBS: the thick ring layers in the transverse plane forms a concentric circle; the crack entered from the surface to the center, rather than along the boundaries of the layers with BB; the surface color presented a more vivid yellow than that of BB. Furthermore, each sample was extracted with ethanol to examine the time course of the change in extract solution color. The maximum optical absorbance of both extract solutions originally showed 415nm in wavelength. However, 24 hours after the preparation, only the peak absorbance of BB was stable. This indicates that the fading speed of ethanol extract solution for CBS was faster. As a result, it was concluded that CBS can be distinguished from BB by the above characteristics.
2008-02-20