Convenient TLC-based Identification Test for the Crude Drug "Pogostemoni Herba"

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概要

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• TLC and HPLC were used to identify possible chemical markers for evaluating the quality of the crude drug "Pogostemoni herba" (aerial part of Pogostemon cablin), which is a component of Kampo medicines. In addition to the reported patchouli alcohol and 2-hydroxy-6-methyl-3-(4-methylpentanoyl)-4-pyrone, three phenylethanoids were isolated from this plant material for the first time: acteoside, isoacteoside, and crenatoside. The usefulness of these compounds as indicators of the crude commercial drug under various TLC conditions was examined, and patchouli alcohol was found to give a definite spot with a reproducible Rf value. Therefore, we propose TLC of the methanol (MeOH) extract using patchouli alcohol as a marker as a convenient method for identifying the crude drug Pogostemoni herba.

• 社団法人日本薬学会の論文
• 2008-12-01

著者

• 御影 雅幸

  金沢大学大学院自然科学研究科薬学系資源生薬学研究室

• 吉田 隆志

  Department Of Pharmacognosy College Of Pharmaceutical Sciences Matsuyama University

• 合田 幸広

  国立医薬品食品衛生研究所

• 吉田 隆志

  岡山大学薬学部

• 川原 信夫

  国立衛研

• 川原 信夫

  医薬基盤研究所薬用植物資源研究センター

• 川原 信夫

  Divition of Pharmacognosy and Phytochemistry, National Institute of Hygienic Sciences

• 天倉 吉章

  College of Pharmaceutical Sciences, Matsuyama University

• 好村 守生

  College of Pharmaceutical Sciences, Matsuyama University

• 毛利 千香

  Graduate School of Natural Science and Technology, Kanazawa University

• 御影 雅幸

  Graduate School of Natural Science and Technology, Kanazawa University

• 川原 信夫

  Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences

• 合田 幸広

  Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences

• 吉田 隆志

  College of Pharmaceutical Sciences, Matsuyama University

• 御影 雅幸

  金沢大学薬学部

• 合田 幸広

  国立医薬品食品衛生研究所生薬部

• 吉田 哲也

  広島大学医学部

• Takahashi Y

  Microbial Chemistry Research Center

• 天倉 吉章

  College Of Pharmaceutical Sciences Matsuyama University

• 御影 雅幸

  Graduate School Of Natural Sci. And Technol. Kanazawa Univ.

• 合田 幸広

  国立医薬品食品衛生研究所 生薬部

• 合田 幸弘

  National Institute Of Health Sciences

• 御影 雅幸

  金沢大学薬学部資源生薬学研究室(薬用植物園)

• Yoshida T

  Department Of Pharmacognosy College Of Pharmaceutical Sciences Matsuyama University

• Takahashi Y

  Research And Development Headquaters Hokuriku Seivaku Co. Ltd.

• Yoshida T

  Hokuriku Seiyaku Co. Ltd. Fukui Jpn

• Yoshida T

  Department Of Microbiology Hiroshima University School Of Medicine

• Yoshida T

  Faculty Of Integrated Arts And Sciences The University Of Tokushima

• 御影 雅幸

  金沢大学大学院自然科学研究科

• 御影 雅幸

  金沢大学 大学院自然科学研究科薬学系資源生薬学研究室

• Yoshida T

  College Of Pharmaceutical Sciences Matsuyama University

• 吉田 隆志

  College Of Pharmaceutical Sciences Matsuyama University

• Yoshida Takuji

  Showa Pharmaceutical University

• 川原 信夫

  National Institute Of Health Sciences

• 天倉 吉章

  松山大学薬学部

• 好村 守生

  松山大学薬学部

• 毛利 千香

  Graduate School Of Natural Science And Technology Kanazawa University

• Mikage M

  Kanazawa Univ. Kanazawa Jpn

• 御影 雅幸

  金沢大 大学院自然科学研究科

• 川原 信夫

  医薬基盤研究所薬用植物資源研究センター筑波研究部

• Yoshida Takashi

  Faculty Of Agriculture And Life Science Hirosaki University

• 川原 信夫

  医薬基盤研 薬用植物資源研究セ

• 御影 雅幸

  金沢大学薬学部附属薬用植物園

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