ニンジンジュースの摂取がヒト血清コレステロール濃度に及ぼす影響

概要

論文の詳細を見る
Carrot contains much β-carotene, which has been shown to act as HMG-CoA reductase inhibitor. We examined the effect of carrot juice drinking on serum cholesterol levels in healthy male volunteers. Daily ingestion with 1 or 2 cans of commercially available carrot juice (160 g/can, β-carotene : 6.6 mg/can) for 4 weeks (Study 2) did not affect on a serum level of total cholesterol, but, feeding of 3 cans of it (Study 1) significantly lowered the serum total cholesterol level (202±26 mg/dl → 189±25 mg/dl). This suggested that the minimum requisite dose of β-carotene to bring a decreased cholesterol level was 20 mg/day in this study. The degree of cholesterol decrease was more significant among the persons whose serum cholesterol level had been over 200 mg/dl at the beginning of the experiment. In all experimental groups, feeding the carrot juice for 4 weeks increased serum level of β-carotene, but there were no statistical changes in the level of serum retinol during the trial period. Those suggested that the carrot juice was safe beverage to drink daily for health promotion. However, the evidences from these results would have some limitation, because Study 1 had no control group, and both studies were not blind trials. Clinical trials for β-carotene and carrot rich in P-carotene in relation to hypocholesterolemic action are scarce. Further studies in human are warranted.
2003-05-23