Immunological Responses in Germfree Mice Infected with Murine Cytomegalovirus
スポンサーリンク
概要
- 論文の詳細を見る
The immunological response of spleen cells was examined during murine cytomegalovirus (MCMV) infection of germfree (GF) mice. GF mice were more susceptible to MCMV infection than specific pathogen-free (SPF) mice. Recovery from the acute phase of MCMV infection was delayed in GF mice as compared to SPF mice. During MCMV infection, the immune response of GF mice, measured in terms of mitogen and of antibody response to sheep erythrocytes, was more markedly depressed and the recovery from the depression was more delayed than in SPF mice. In MCMV-infected mice, natural killer (NK) cell activity was increased by day 1 and 2 post-infection, with similar kinetics in GF and SPF mice, suggesting that NK cells may be exerting the most potent antiviral effect during the early stage of MCMV infection.
- 東海大学の論文
著者
-
Yoshida Takahiko
Department of Health Science, Asahikawa Medical Collage
-
ANDO Kiyoshi
Department of Hematology/Oncology, Tokai University School of Medicine
-
Leung Wai
Department Of Microbiology Tokai University School Of Medicine
-
UMEHARA Keiko
Department of Microbiology, School of Medicine, Tokai University
-
HASHIMOTO Kazuo
Department of Microbiology, School of Medicine, Tokai University
-
Hashimoto Kazuo
Department Of Microbiology Tokai University School Of Medicine
-
Hashimoto Kazuo
Department Of Microbiology School Of Medicine Tokai University
-
Yoshida Takahiko
Department Of Environmental Health Division Of Community And Environmental Health Tokai University S
-
Ando Kiyoshi
Department Of Microbiology School Of Medicine Tokai University
-
Umehara Keiko
Department Of Microbiology School Of Medicine Tokai University
-
Umehara Keiko
Department Of Microbiology Tokai University School Of Medicine
-
TAZUME Seiki
Department of Microbiology, School of Medicine, Tokai University
-
Hashimoto K
Department Of Microbiology Tokai University School Of Medicine
-
Tazume S
Tokai University School Of Health Sciences
-
Ando Kiyoshi
Department Of Hematology And Oncology Tokai University School Of Medicine
-
Yoshida Takahiko
Department Of Environmental Medicine And Occupational Health School Of Medicine Tokai University
-
Leung Wai
Department Of Medicine And Therapeutics The Chinese University Of Hong Kong
-
Ando Kiyoshi
Department Of Hematology And Oncology Tokai University
-
TAZUME Seiki
Department of Microbiology School of Medicine, Tokai University
関連論文
- Comparative analysis of remission induction therapy for high-risk MDS and AML progressed from MDS in the MDS200 study of Japan Adult Leukemia Study Group
- Persistence of derivative chromosome 22 after achieving a major molecular response in chronic myeloid leukemia with a cryptic BCR-ABL1 fusion gene
- PE-376 Repeated Intermittent Thermal Therapy Enhances Antioxidative Property and Attenuates Atherosclerosis in Patients with Hypertension(Atherosclerosis, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Phase I and II pharmacokinetic and pharmacodynamic study of the proteasome inhibitor bortezomib in Japanese patients with relapsed or refractory multiple myeloma
- Non-hematopoietic Mesenchymal Stem Cells can be Mobilized and Differentiate into Cardiomyocytes after Myocardial Infarction(Development and Differentiation 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Transplanted Bone Marrow Stem Cells Move to the Infarcted Myocardium and Regenerate the Heart
- Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages
- A METHOD FOR ESTIMATION OF HEPATIC DRUG-METABOLIZING CAPACITY : DETERMINATION OF CONCENTRATION OF TRIMETHADIONE AND ITS METABOLITE IN HUMAN SERUM
- Magnetization Measurement of NENP and NINO in High Magnetic Field
- Prognostic Significance of FLT3 Internal Tandem Duplication and NPM1 Mutations in Acute Myeloid Leukemia in an Unselected Patient Population
- Prospective isolation of regenerated cardiomyocytes from the mixture of mesenchymal stem cells
- CORRELATION BETWEEN SEVERITY OF PARKINSONISM AND DOPAMINE NEURONAL DAMAGE IN MPTP-TREATED MARMOSETS
- Ex vivo evidence for asymmetric tyrosine phosphorylation of ZAP-70 on double-positive thymocytes in the positive selection process
- Intermediate Valence State of La_Eu_Ni_2(Si_Ge_x)_2 Compounds (Condensed Matter: Electronic Structure, Electrical, Magnetic and Optical Properties)
- ^Al Nuclear Magnetic Relaxation Studies of Spin Fluctuation in Ual_2
- ^P Nuclear Magnetic Relaxation Studies of the Dynamical Magnetic Behavior of UP
- Inflammation as a cardiovascular risk factor and pulse wave velocity as a marker of early-stage atherosclerosis in the Japanese population
- Trial of Isolation of a Virus from Sera of Patients with Kawasaki Disease
- 3 Lesson from GFP^+ bone marrow transplanted mice : Regeneration of infarcted myocardium by cytokine administration(Symposium 8 (SY8) (M) : Regeneration Medicine of Cardiovascular Diseases)(Special Program)
- 3-Dimensional Coronary Angiography in Mice Using Confocal : Laser Scanning Microscopy
- 簡易な半定量的ダニアレルゲン検査の比較研究
- Survey of Food and Airborne Allergen-specific IgE Levels in a General Population of 3-year-old Japanese Children
- TISSUE- AND DOSE-DEPENDENT ALTERATION OF STRESS-INDUCIBLE PROTEINS BY β_2-ADRENOCEPTOR AGONIST, SALBUTAMOL, IN RATS
- QUANTITATIVE ESTIMATION OF MYOCARDIAL FIBROSIS BASED ON RECEPTOR OCCUPANCY FOR β_2-ADRENERGIC RECEPTOR AGONISTS IN RATS
- Establishment and Peculiarity of Ouabain-resistant THP-1 cells
- INITIAL METABOLISM OF GAMMA-HEXACHLOROCYCLOHEXANE (γ-HCH) BY RAT LIVER MICROSONES
- ALTERATIONS OF HEPATIC MITOCHONDRIAL MONOAMINE OXIDASE ACTIVITY OF RATS DURING 2-ACETYLAMINOFLUORENE FEEDING
- Relation of dampness to sick building syndrome in Japanese public apartment houses
- Chronic exposure to sodium arsenite causes fibrogenic changes in the skin of mice, and short-term exposure may show anti-fibrogenic effects on fibroblast cells
- Prevalence of Burnout among Public Health Nurses in Charge of Mental Health Services and Emergency Care Systems in Japan
- Induction and Inhibition of Cytochrome P450 and Drug-Metabolizing Enzymes by Climbazole
- P12-08 Effect of 4-(4-Chlorobenzyl)pyridine on Rat Hepatic Microsomal Cytochrome P450 and Drug-metabolizing Enzymes In Vivo and In Vitro
- CLIMBAZOLE IS A NEW POTENT INDUCER OF RAT HEPATIC CYTOCHROME P450
- Effect of 4-(4-Chlorobenzyl)pyridine on Rat Hepatic Microsomal Cytochrome P450 and Drug-Metabolizing Enzymes in Vivo and in Vitro
- SEX-RELATED EFFECT OF HEMIN ON CYTOCHROME P450 AND DRUG-METABOLIZING ENZYMES IN RAT LIVER
- Interleaving-Based Multiple Access and Iterative Chip-by-Chip Multiuser Detection(Wireless Communication Technology)
- Birefringence Induced by Lattice Imperfections in the Paraelectric Phase of KH_2PO_4
- Orientations of the Optical Indicatrices of KH_2PO_4 and NH_4H_2PO_4 in Their Low Temperature Phases
- The Use of Docosahexaenoic Acid Supplementation to Ameliorate the Hyperactivity of Rat Pups Induced by in utero Ethanol Exposure
- Effects of Ethyl Alcohol Administration to Rat Dams during the Gestation Period on Learning Behavior and on Levels of Monoamines and Metabolites in Rat Pup Brain after Birth
- Calcium Induced Differentiation of SV40 Immortalized Human Epidermal Keratinocytes Cultured in a Defined Medium
- Strain Difference in Learning Impairment in Rats following Lead Administration during Brain Development
- Regulation of ERK-Mediated Signal Transduction by p38 MAP Kinase in Human Monocytic THP-1 Cells
- INDUCTION OF HEPATIC CYP2B1/2 BY A TERATOGENIC COMPOUND cis-1-[-4-P-MENTHANE-8-YLOXY)PHENYL]PIPERADINE(YM9429)IN RATS
- Mechanism of Heme Oxygenase-1 (HO-1) Induction by a Glutathione Depletor, Phorone in Rar Livers
- Selective Inhibition of Chondrogenic Differentiation in Embryonic Cells by a Teratogenic Compound
- "B-10 MECHANISM OF HEME OXYGENASE-1 (HO-1) INDUCTION UNDER OXIDATIVE STRESS EVOKED BY A GLUTATHIONE DEPLETOR, PHORONE, IN RAT LIVERS.
- Possible Role of Glutathione Depletion in the Induction of Rate-Limiting Enzymes Involved in Heme Degradation and Polyamine Biosynthesis in the Liver of Rats
- A RAPID MICROASSAY FOR HEMOLYTIC ANTIBODY : ITS APPLICATION TO IMMUNOTOXICOLOGICAL STUDY
- Comparative Studies on the Inducing Effects of Cobalt Chloride and Co-Protoporphyrin on Hepatic Ornithine Decarboxylase and Heme Oxygenase in Rats
- DEPLETION OF HEPATIC GLUTATHIONE IS FOLLOWED BY THE INDUCTION OF HEME OXYGENASE AND CHANGES IN DRUG-METABOLIZING ENZYMES
- Relationship between Hepatic Glutathione Consumption and the Induction of Enzymes Involved in Polyamine Biosynthesis Evoked by Various Drugs and Chemicals (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
- Immunological Effects of Arsenic Compounds on Mouse Spleen Cells in vitro
- EVALUATION OF THE INDUCTION OF HEPATIC DRUG-METABOLIZING ENZYMES IN THE RAT AND MOUSE TREATED WITH TEMAZEPAM USING TRIMETHADIONE AS THE INDICATOR
- RELATIONSHIP BETWEEN TRIMETHADIONE METABOLISM AND HEPATIC DRUG-OXIDIZING ENZYME ACTIVITIES IN DIFFERENT ANIMAL SPECIES
- STUDIES ON THE TRIMETHADIONE METABOLISM AS A TOOL FOR THE ASSESSMENT OF DRUG-METABOLIZING CAPACITY USING PLASMA AND URINE OF RATS PRETREATED WITH PHENOBARBITAL AND 3-METHYLCHOLANTHRENE
- DETERMINATION OF PLASMA TRIMETHADIONE AND ITS METABOLITE IN CARBON TETRACHLORIDE-INTOXICATED RATLIVER : A USEFUL TOOL FOR ESTIMATION OF HEPATIC DRUGMETABOLIZING CAPACITY
- SALIVA LEVELS OF TRIMETHADIONE AND ITS METABOLITE AS AN INDEX OF DRUG METABOLIZING ACTIVITY IN RATS
- Concurrent Murine Cytomegalovirus and Klebsiella pneumoniae Infections in Germfree Mice
- Immunological Responses in Germfree Mice Infected with Murine Cytomegalovirus
- Phase II study of oral fludarabine in combination with rituximab for relapsed indolent B-cell non-Hodgkin lymphoma
- Crystal structures of betaine phosphate/Arsenate mixed crystal
- Crystal structure and phase transition at low temperature in betaine phosphate
- XAFS Study on the Structure of Ytterbium(III)Trifluoromethanesulfonates as a New Type Catalyst (Proceedings of the Second International Conference on SRMS(Synchrotron Radiation in Materials Science)(2))
- Human CD34^- Hematopoietic Stem Cells: Basic Features and Clinical Relevance
- Murine Cytomegalovirus Infection Model in Balb/c Mice : 3. Immunoglobulin Production during Infection
- Murine Cytomegalovirus Infection Model in Balb/c Mice : 2. Pericarditis with Myocardial Involvement during Virus Infection
- Murine Cytomegalovirus Infection Model in Balb/c Mice : 1. Virological and Pathological Profiles in Mice Inoculated with Various Virus Doses
- Changes in the Amounts of Neurotransmitters Released from the Striatum and Spontaneous Motor Activity in Rats Exposed to High Doses of Toluene
- Advantageous animal model "THA" for neurotoxicological or neuropharmacological study
- Inhibitory Effects of Bovine Lactoferrin on the Adherence of Enterotoxigenic Escherichia coli to Host Cells
- ON n-TH VON NEUMANN-JORDAN CONSTANTS FOR BANACH SPACES
- Generalized Clarkson's Inequalities for Lebesgue-Bochner Spaces
- Environmental Estrogens Increase Expression of SS-A/Ro Autoantigen in Normal Human Epidermal Keratinocytes
- SIMULTANEOUS INDUCTION OF ORNITHINE DECARBOXYLASE AND HEME OXYGENASE UNDER VARIOUS EXPERIMENTAL CONDITIONS
- The Mode of Induction of Ornithine Decarboxylase by Heavy Metals (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations)
- Characteristics of CD5-Positive Splenic Marginal Zone Lymphoma with Leukemic Manifestation ; Clinical, Flow Cytometry, and Histopathological Findings of 11 Cases
- Association between lifestyle habits and bone mineral density in Japanese juveniles（日本人若年者における生活習慣と骨塩密度の関連）
- Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma
- Effect of Zinc Deficiency on the Behavior of Metallothionein-I, II Knockout Mice
- Intestinal Bacterial Flora and Host Defense Mechanisms
- Cyclic AMP and Immune Responses: Identification of Prostaglandin E-Producing Cells in Mouse Spleens
- Antigenic Competition : Suppression of the Response to a First Antigen by a Second Antigen
- Cyclic AMP and Immune Responses : Cytochemical Identification and Localization of Adenylate Cyclase Responding Cells in Antigen-Stimulated Mouse Spleen
- Analysis of Antiviral Resistance in the Intestinal Tracts of Nude Mice Infected with a Mouse Adenovirus
- Normalization of Reproductive Function in Germfree Mice Following Bacterial Contamination
- Induction of Ornithine Decarboxylase by Heavy Metals : With Special Reference to Cadmium (Regular Presentations) (Proceedings of the 11 th Symposium on Environmental Pollutants and Toxicology)
- EFFECTS OF CHRONIC ADMINISTRATION OF KANAMYCIN ON CONDITIONED SUPPRESSION TO AUDITORY STIMULUS IN RATS
- THE RELATIONSHIP BETWEEN MORTALITY OF STROKE AND TRACE METAL ELEMENTS
- 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro
- Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria : the AEGIS Clinical Trial
- Lack of non-hematological cross intolerance of dasatinib to imatinib in imatinib-intolerant patients with Philadelphia chromosome positive chronic myeloid leukemia or acute lymphatic leukemia : a retrospective safety analysis
- MicroRNAs expression in the Ethylene Glycol Monomethyl Ether-induced testicular lesion
- Romiplostim for the treatment of chronic immune thrombocytopenia in adult Japanese patients : a double-blind, randomized Phase III clinical trial
- A respiratory sensitization study by a new quantitative structure-activity relationships (QSAR)
- Dampness, food habits, and sick building syndrome symptoms in elementary school pupils
- Experimental Analysis of Concurrent Viral and Bacterial Infection in the Mouse
- 6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta
- Equivariant local index (Geometry of Transformation Groups and Combinatorics)