Effects of Ethyl Alcohol Administration to Rat Dams during the Gestation Period on Learning Behavior and on Levels of Monoamines and Metabolites in Rat Pup Brain after Birth
スポンサーリンク
概要
- 論文の詳細を見る
Pregnant rats were given 0%-, 5%-, 10%- and 20% ethyl alcohol in drinking water during the gestation period. We evaluated the brain function of pups born of alcohol-administered dams. Learning ability (Sidman avoidance behavior), the amounts of monoamines (noradrenalin, dopamine, serotonin) and metabolites (3, 4-dihydroxyphenyl acetic acid [DOPAC], homovanillic acid [HVA] and 5-hydroxyindole acetic acid [5-HIAA]) in whole brain were examined for neurobehavioral and neurochemical effects. There was no effect on Sidman avoidance behavior in 56-day-old offspring, but alterations of the amounts of monoamines and their metabolites were observed even in 66-day-old offspring as a result of the dams' exposure to ethanol during pregnancy.
- 日本衛生学会の論文
著者
-
Aikawa Hiroyuki
Department Of Environmental Health Tokai University School Of Medicine
-
Aikawa Hiroyuki
Department Of Occupational Health And Industrial Hygine School Of Medicine Tokai University
-
Okazaki I
Department Of Community Health Tokai University School Of Medicine
-
Yoshida T
Department Of Biochemical Toxicology School Of Pharmaceutical Science Showa University
-
Aikawa Hiroyuki
Department Of Basic Clinical Science And Public Health Tokai University School Of Medicine
-
Aikawa Hiroyuki
Department Of Environmental Health Division Of Community And Environmental Health Tokai University S
-
Yoshida Takahiko
Department Of Environmental Health Division Of Community And Environmental Health Tokai University S
-
Yoshida Takahiko
Department Of Environmental Medicine And Occupational Health Tokai University School Of Medicine
-
Aikawa H
Tokai Univ. School Of Medicine
-
FURUYA Hiroyuki
Division of Community and Environmental Health, Department of Environmental Health, Tokai University
-
AIKAWA Hiroyuki
Division of Community and Environmental Health, Department of Environmental Health, Tokai University
-
YOSHIDA Takahiko
Division of Community and Environmental Health, Department of Environmental Health, Tokai University
-
OKAZAKI Isao
Division of Community and Environmental Health, Department of Community Health, Tokai University Sch
-
Furuya H
Takai Univ. School Of Medicine Kanagawa Jpn
-
Yoshida Tomoko
Department of Biochemical Toxicology, School of Pharmacy Showa University
関連論文
- PE-376 Repeated Intermittent Thermal Therapy Enhances Antioxidative Property and Attenuates Atherosclerosis in Patients with Hypertension(Atherosclerosis, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Role of TIMPs in the recovery from liver fibrosis in rat
- RHO FAMILY GTPASES REGULATE TRANSCRIPTIONAL INDUCTION OF MATRIX METHALLOPROTEINASE-1 BY TUMOR NECROSIS FACTOR α IN HUMAN HEPATIC STELLATE CELLS.
- DYNAMIC CHANGE OF CELLS EXPRESSING MMP-2 mRNA AND MT1-MMP mRNA IN THE RECOVERY FROM RAT LIVER FIBROSIS
- Salbutamol inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal macrophages
- Pigpen, a nuclear coiled body component protein, is involved in angiogenesis
- Acute hepatitis in an adult with acquired rubella infection
- A METHOD FOR ESTIMATION OF HEPATIC DRUG-METABOLIZING CAPACITY : DETERMINATION OF CONCENTRATION OF TRIMETHADIONE AND ITS METABOLITE IN HUMAN SERUM
- Perceived Sleepiness of Non-Shift Working Men in Two Different Types of Work Organization
- Magnetization Measurement of NENP and NINO in High Magnetic Field
- Expression and Subcellular Localization of Candida tropicalis Catalase in Catalase Gene Disruptants of Saccharomyces cerevisiae
- Individual Expression of Candida tropicalis Peroxisomal and Mitochondrial Carnitine Acetyltransferase-Encoding Genes and Subcellular Localization of the Products in Saccharomyces cerevisiae
- Intermediate Valence State of La_Eu_Ni_2(Si_Ge_x)_2 Compounds (Condensed Matter: Electronic Structure, Electrical, Magnetic and Optical Properties)
- Diagnostic Nano-Analysis of Materials Properties by Multivariate Curve Resolution Applied to Spectrum Images by S/TEM-EELS
- ^Al Nuclear Magnetic Relaxation Studies of Spin Fluctuation in Ual_2
- ^P Nuclear Magnetic Relaxation Studies of the Dynamical Magnetic Behavior of UP
- Inflammation as a cardiovascular risk factor and pulse wave velocity as a marker of early-stage atherosclerosis in the Japanese population
- Urinary Hippuric Acid Excretion in Everyday Life
- Urinary Hippuric Acid Excretion after Use of Spray Ski-wax and Remover
- 簡易な半定量的ダニアレルゲン検査の比較研究
- Survey of Food and Airborne Allergen-specific IgE Levels in a General Population of 3-year-old Japanese Children
- Subcellular Destination of Mutant Peroxisomal Isocitrate Lyase Polypeptides of Candida tropicalis in Saccharomyces cerevisiae
- TISSUE- AND DOSE-DEPENDENT ALTERATION OF STRESS-INDUCIBLE PROTEINS BY β_2-ADRENOCEPTOR AGONIST, SALBUTAMOL, IN RATS
- QUANTITATIVE ESTIMATION OF MYOCARDIAL FIBROSIS BASED ON RECEPTOR OCCUPANCY FOR β_2-ADRENERGIC RECEPTOR AGONISTS IN RATS
- Establishment and Peculiarity of Ouabain-resistant THP-1 cells
- INITIAL METABOLISM OF GAMMA-HEXACHLOROCYCLOHEXANE (γ-HCH) BY RAT LIVER MICROSONES
- ALTERATIONS OF HEPATIC MITOCHONDRIAL MONOAMINE OXIDASE ACTIVITY OF RATS DURING 2-ACETYLAMINOFLUORENE FEEDING
- Relation of dampness to sick building syndrome in Japanese public apartment houses
- Chronic exposure to sodium arsenite causes fibrogenic changes in the skin of mice, and short-term exposure may show anti-fibrogenic effects on fibroblast cells
- Prevalence of Burnout among Public Health Nurses in Charge of Mental Health Services and Emergency Care Systems in Japan
- Induction and Inhibition of Cytochrome P450 and Drug-Metabolizing Enzymes by Climbazole
- P12-08 Effect of 4-(4-Chlorobenzyl)pyridine on Rat Hepatic Microsomal Cytochrome P450 and Drug-metabolizing Enzymes In Vivo and In Vitro
- CLIMBAZOLE IS A NEW POTENT INDUCER OF RAT HEPATIC CYTOCHROME P450
- Effect of 4-(4-Chlorobenzyl)pyridine on Rat Hepatic Microsomal Cytochrome P450 and Drug-Metabolizing Enzymes in Vivo and in Vitro
- SEX-RELATED EFFECT OF HEMIN ON CYTOCHROME P450 AND DRUG-METABOLIZING ENZYMES IN RAT LIVER
- Seroprevalence of Bartonella henselae in Patients with Uveitis and Healthy Individuals in Tokyo
- Birefringence Induced by Lattice Imperfections in the Paraelectric Phase of KH_2PO_4
- Orientations of the Optical Indicatrices of KH_2PO_4 and NH_4H_2PO_4 in Their Low Temperature Phases
- The Use of Docosahexaenoic Acid Supplementation to Ameliorate the Hyperactivity of Rat Pups Induced by in utero Ethanol Exposure
- Effects of Ethyl Alcohol Administration to Rat Dams during the Gestation Period on Learning Behavior and on Levels of Monoamines and Metabolites in Rat Pup Brain after Birth
- Strain Difference in Learning Impairment in Rats following Lead Administration during Brain Development
- Regulation of ERK-Mediated Signal Transduction by p38 MAP Kinase in Human Monocytic THP-1 Cells
- INDUCTION OF HEPATIC CYP2B1/2 BY A TERATOGENIC COMPOUND cis-1-[-4-P-MENTHANE-8-YLOXY)PHENYL]PIPERADINE(YM9429)IN RATS
- Mechanism of Heme Oxygenase-1 (HO-1) Induction by a Glutathione Depletor, Phorone in Rar Livers
- Selective Inhibition of Chondrogenic Differentiation in Embryonic Cells by a Teratogenic Compound
- "B-10 MECHANISM OF HEME OXYGENASE-1 (HO-1) INDUCTION UNDER OXIDATIVE STRESS EVOKED BY A GLUTATHIONE DEPLETOR, PHORONE, IN RAT LIVERS.
- Possible Role of Glutathione Depletion in the Induction of Rate-Limiting Enzymes Involved in Heme Degradation and Polyamine Biosynthesis in the Liver of Rats
- A RAPID MICROASSAY FOR HEMOLYTIC ANTIBODY : ITS APPLICATION TO IMMUNOTOXICOLOGICAL STUDY
- Comparative Studies on the Inducing Effects of Cobalt Chloride and Co-Protoporphyrin on Hepatic Ornithine Decarboxylase and Heme Oxygenase in Rats
- DEPLETION OF HEPATIC GLUTATHIONE IS FOLLOWED BY THE INDUCTION OF HEME OXYGENASE AND CHANGES IN DRUG-METABOLIZING ENZYMES
- Relationship between Hepatic Glutathione Consumption and the Induction of Enzymes Involved in Polyamine Biosynthesis Evoked by Various Drugs and Chemicals (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology)
- Immunological Effects of Arsenic Compounds on Mouse Spleen Cells in vitro
- EVALUATION OF THE INDUCTION OF HEPATIC DRUG-METABOLIZING ENZYMES IN THE RAT AND MOUSE TREATED WITH TEMAZEPAM USING TRIMETHADIONE AS THE INDICATOR
- RELATIONSHIP BETWEEN TRIMETHADIONE METABOLISM AND HEPATIC DRUG-OXIDIZING ENZYME ACTIVITIES IN DIFFERENT ANIMAL SPECIES
- STUDIES ON THE TRIMETHADIONE METABOLISM AS A TOOL FOR THE ASSESSMENT OF DRUG-METABOLIZING CAPACITY USING PLASMA AND URINE OF RATS PRETREATED WITH PHENOBARBITAL AND 3-METHYLCHOLANTHRENE
- DETERMINATION OF PLASMA TRIMETHADIONE AND ITS METABOLITE IN CARBON TETRACHLORIDE-INTOXICATED RATLIVER : A USEFUL TOOL FOR ESTIMATION OF HEPATIC DRUGMETABOLIZING CAPACITY
- SALIVA LEVELS OF TRIMETHADIONE AND ITS METABOLITE AS AN INDEX OF DRUG METABOLIZING ACTIVITY IN RATS
- Immunological Responses in Germfree Mice Infected with Murine Cytomegalovirus
- Crystal structures of betaine phosphate/Arsenate mixed crystal
- Crystal structure and phase transition at low temperature in betaine phosphate
- Anesthesia and Acoustic Stress-Induced Intra-Uterine Growth Retardation in Mice
- XAFS Study on the Structure of Ytterbium(III)Trifluoromethanesulfonates as a New Type Catalyst (Proceedings of the Second International Conference on SRMS(Synchrotron Radiation in Materials Science)(2))
- Structure Formation of' Isotactic Polypropylene from the Glass : Condensed Matter: Structure, etc.
- Changes in the Amounts of Neurotransmitters Released from the Striatum and Spontaneous Motor Activity in Rats Exposed to High Doses of Toluene
- Advantageous animal model "THA" for neurotoxicological or neuropharmacological study
- Repeated Toluene Exposure and Sidman Avoidance Response in Rats
- EFFECT OF SINGLE EXPOSURE TO TOLUENE ON SIDMAN AVOIDANCE RESPONSE IN RATS
- Spectral restoration and energy resolution improvement of electron energy-loss spectra by Pixon reconstruction : II. Application to practical ELNES analysis of low SNR
- Environmental Estrogens Increase Expression of SS-A/Ro Autoantigen in Normal Human Epidermal Keratinocytes
- EFFECTS OF POSTNATAL LOW-LEVELS OF EXPOSURE TO STYRENE ON BEHAVIOR AND DEVELOPMENT IN RATS
- SIMULTANEOUS INDUCTION OF ORNITHINE DECARBOXYLASE AND HEME OXYGENASE UNDER VARIOUS EXPERIMENTAL CONDITIONS
- The Mode of Induction of Ornithine Decarboxylase by Heavy Metals (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations)
- Effects of Maternal Exposure to Toluene during Pregnancy on Mouse Embryos and Fetuses
- EFFECTS OF TOLUENE EXPOSURE ON MICE FETUSES
- LEAD TRANSFER FROM MOTHER TO OFFSPRING IN RATS (The Fourth Meeting for the Study of Toxic Effect)
- Effect of Lead on Operant Behaviour in Rats
- Association between lifestyle habits and bone mineral density in Japanese juveniles（日本人若年者における生活習慣と骨塩密度の関連）
- Reversibility of hepatic fibrosis : from the first report of collagenase in the liver to the possibility of gene therapy for recovery
- Effect of Zinc Deficiency on the Behavior of Metallothionein-I, II Knockout Mice
- Continuous Synthesis of a Tripeptide by Successive Condensation and Transesterification Catalyzed by Two Immobilized Proteinases in Organic Solvent(Microbiology & Fermentation Industry)
- In-Situ Optical Reflection Measurement of a Si(100) Surface under Hydrogen Ion Irradiation
- Induction of Ornithine Decarboxylase by Heavy Metals : With Special Reference to Cadmium (Regular Presentations) (Proceedings of the 11 th Symposium on Environmental Pollutants and Toxicology)
- CD35 expression on peripheral blood granulocytes of patients with atopic dermatitis
- 在胎週数33週未満の児に対する経皮酸素飽和度目標設定値変更と未熟児網膜症との関係
- MicroRNAs expression in the Ethylene Glycol Monomethyl Ether-induced testicular lesion
- A respiratory sensitization study by a new quantitative structure-activity relationships (QSAR)
- Dampness, food habits, and sick building syndrome symptoms in elementary school pupils
- Tokai High Avoider rat (THA rat) that maintains an inborn high learning ability : Its application to screening of environmental factors with neurobehavioral effects
- 6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta
- Equivariant local index (Geometry of Transformation Groups and Combinatorics)
- Individual Expression of Candida tropicalis Peroxisomal and Mitochondrial Carnitine Acetyltransferase-Encoding Genes and Subcellular Localization of the Products in Saccharomyces cerevisiae.