Pituicytoma : Two Case Reports
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概要
- 論文の詳細を見る
Pituicytoma is a rare tumor in the sellar or suprasellar region with distinct histological characteristics of glial neoplasm. A 42-year-old woman presented with a history of amenorrhea and vertigo, and a 62-year-old woman presented with mild headache. Both patients had mild hyperprolactinemia and one had mild anterior pituitary dysfunction. They underwent transcranial partial resection of a suprasellar tumor. The tumors were characterized by storiform pattern of elongated cells immunoreactive for S-100 protein and glial fibrillary acidic protein. Ultrastructural study showed abundant cytoplasmic intermediate filaments and tumor/blood vessel basal lamina, but no desmosomes between tumor cells. The residual tumors showed no changes in size without adjuvant therapy at 56 and 18 months after surgery. Pituicytoma is a glial neoplasm of adults with low proliferative activity. Patients often present with visual symptoms or anterior pituitary dysfunction. Symptoms and signs of neurohypophysis are rare. Neuroimaging reveals an intra- or suprasellar mass with non-specific features. The prognosis and role of adjuvant therapy remain unclear for this discrete noninfiltrative glioma.
- 日本脳神経外科学会の論文
- 2006-03-15
著者
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SAITO AKIRA
Department of Pediatrics, Hirosaki University School of Medicine
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Kameya Toru
Pathology Division Shizuoka Cancer Center Hospital And Research Institute
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NAKASU Yoko
Division of Neurosurgery, Shizuoka Cancer Center
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NAKASU SATOSHI
Department of Neurosurgery, Molecular Neurobiology Research Centre, Shiga University of Medical Scie
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Kameya Toru
Pathology Shizuoka Cancer Center
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HORIGUCHI Satoshi
Divisions of Neurosurgery, Shizuoka Cancer Center
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Horiguchi Satoshi
Divisions Of Neurosurgery Shizuoka Cancer Center
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Kameya Toru
Pathology Division National Cancer Center Resaerch Institute
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Nakasu Yoko
Divisions Of Neurosurgery Shizuoka Cancer Center
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Nakasu Yoko
Division Of Neurosurgery Shizuoka Cancer Center
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Nakasu Satoshi
Department Of Neurosurgery Shiga University Of Medical Science
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Nakasu Yoko
Department Of Neurosurgery Molecular Neurobiology Research Centre Shiga University Of Medical Scienc
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Horiguchi Satoshi
Division Of Neurosurgery Shizuoka Cancer Center
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Nakasu Yoko
Department Of Neurosurgery Molecular Neurobiology Research Centre Shiga University Of Medical Scienc
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Saito Akira
Department Of Pathology Juntendo University Urayasu Hospital
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Saito Akira
Department Of Neurosurgery Nagahama Red Cross Hospital
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Saito Akira
Department of Biological Chemistry, Yamaguchi University
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Saito Akira
Department of Applied and Bioapplied Chemistry, Graduate School of Engineering, Osaka City University
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