Photodecomposition and Bioconcentration of a Bisphenol A Metabolite in Medaka, Oryzias latipes

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概要

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• Exposure experiments in medaka and photodecomposition tests were performed using a metabolite of bisphenol A [4-methyl-2,4-bis(p-hydroxyphenyl)-pent-1-ene; MBP], the solubility limit of which is 42 mg/l of water. Three adult medaka were kept in a 2 l glass beaker at 25 ± 1°C for 4 days. The LC50 for 96 hr was > 1000 ppb. The measured average MBP concentration in the breeding water (nominal concentration of 100 ppb) was 49.2 ppb. The average concentration in the whole bodies of medaka after 4 days was 1.92 mg/g-wet body, and the bioconcentration factor (BCF) of MBP was calculated to be 39.0. MBP in water and acetone was decomposed very easily, with about 98% of the MBP being decomposed after several hours under sunlight. MBP was also decomposed after 48 hr of illumination under a white fluorescent lamp.

• 公益社団法人日本薬学会の論文
• 2004-12-01

著者

• TAKAO Yuji

  Faculty of Environmental Studies, Nagasaki University

• ARIZONO Koji

  Environmental and Symbiotic Sciences, Prefectural University of Kumamoto

• ARIZONO Koji

  Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto

• Kohra Shinya

  Faculty of Environmental Studies, Nagasaki University

• Tominaga Nobuaki

  Department of Chemical and Biological Engineering, Ariake National College of Technology

• 石橋 康弘

  Environmental And Symbiotic Sciences Prefectural University Of Kumamoto

• Ishibashi Hiroshi

  Faculty Of Engineering Yokohama National University

• Kohra Shinya

  Faculty Of Environmental Studies Nagasaki University

• Kohra Shinya

  Faculty Of Liberal Arts Nagasaki University

• Arizono K

  Prefectural Univ. Kumamoto Kumamoto Jpn

• Arizono Koji

  Environmental And Symbiotic Sciences Prefectural University Of Kumamoto

• Arizono K

  Faculty Of Pharmaceutical Sciences Nagasaki University

• Arizono Koji

  Faculty Of Environment Studies Nagasaki University

• Soyano K

  Nagasaki Univ. Nagasaki

• Soyano Kiyoshi

  Institute For East China Sea Research Nagasaki University

• Soyano Kiyoshi

  Graduate School Of Science And Technology

• Takao Y

  Faculty Of Environmental Studies Nagasaki University

• Takao Yuji

  Faculty Of Environmental Studies Nagasaki University

• 冨永 伸明

  Department Of Chemical And Biological Engineering Ariake National College Of Technology

• Shimazu Miki

  Faculty of Environmental Studies, Nagasaki University

• Nagae Masaki

  Faculty of Environmental Studies, Nagasaki University

• Ishibashi Yasuhiro

  Faculty of Human Environment, Nagasaki Institute of Applied Science

• Ishibashi Yasuhiro

  Environmental Protection Center, Nagasaki University

• Yoshihara Shinichi

  Graduate School of Biomedical Sciences, Hiroshima University

• Saito Koji

  Division Of Marine Biosciences Graduate School Of Fisheries Sciences Hokkaido University

• Tominaga Nobuaki

  Department Of Biochemistry School Of Pharmaceutical Sciences Nagasaki University

• Yoshihara Shinchi

  Faculty Of Pharmaceutical Sciences Kyushu University

• Shimazu Miki

  Faculty Of Environmental Studies Nagasaki University

• Nagae M

  Faculty Of Environmental Studies Nagasaki University

• Nagae Masaki

  Faculty Of Environmental Studies Nagasaki University

• Yoshihara Shinichi

  Faculty Of Pharmaceutical Sciences Kyushu University

• Yoshihara S

  Department Of Xenobiotic Metabolism And Molecular Toxicology Graduate School Of Biomedical Science H

• Ishibashi Hiroshi

  Graduate School Of Science And Technology Nagasaki University

• Ishibashi Yasuhiro

  Faculty Of Human Environment Nagasaki Institute Of Applied Science

• Ishibashi Yasuhiro

  Environmental Protection Center Nagasaki University

• Tominaga Nobuaki

  Dep. Of Chemical And Biological Engineering Ariake National Coll. Of Technol.

• Kohra S

  Faculty Of Environmental Sciences Nagasaki University

• Yoshihara Shinich

  Graduate School of Biomedical Sciences, Hiroshima University

• Ishibashi Yasuhiro

  Environmental Protection Center

• Takao Yuji

  Faculty of Environmental Sciences

• Kohra Shinya

  Faculty of Environmental Sciences

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