Acute toxicity of pharmaceutical and personal care products on freshwater crustacean (Thamnocephalus platyurus) and fish (Oryzias latipes)
スポンサーリンク
概要
- 論文の詳細を見る
Pharmaceutical and personal care products (PPCPs) enter aquatic environments via sewage treatment facilities and their potentially toxic effects on biota, particularly aquatic organisms, are of considerable concern. In this study, we investigated the acute toxicity of selected PPCPs on a freshwater crustacean (Thamnocephalus platyurus) and a fish species (Oryzias latipes). The 24-hr median lethal concentration (LC_<50>) values of ibuprofen, mefenamic acid, indometacin, carbamazepine, propranolol, ifenprodil, clarithromycin and triclosan for T. platyurus were estimated to be 19.59, 3.95, 16.14,>100, 10.31, 4.43, 94.23 and 0.47mg/l respectively. Conversely, the 96-hr LC_<50> values for these PPCPs were estimated at >100, 8.04, 81.92, 45.87, 11.40, 8.71,>100 and 0.60mg/l for O. latipes, respectively. The toxic sensitivity of T. platyurus to these PPCPs, except for carbamazepine, was therefore higher than for O. latipes. No acute toxicity effects were associated with PPCPs, such as atenolol, disopyramide, famotidine, fluconazole, erythromycin and levofloxacin, in the two aquatic organisms at the concentrations tested in this study (>100mg/l). These findings may help us to understand the potential biological effects and risks associated with PPCP exposure in aquatic organisms. Further long-term studies are required to fully assess the growth and reproduction of these compounds on aquatic biota.
- 日本トキシコロジー学会の論文
- 2009-04-01
著者
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KIM Joon-Woo
Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
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ISHIBASHI Hiroshi
Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
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HIRANO Masashi
Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
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TAKAO Yuji
Faculty of Environmental Studies, Nagasaki University
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ICHIKAWA Nobuhiro
College of Pharmaceutical Sciences, Ritsumeikan University
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ARIZONO Koji
Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
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Kim Joon-woo
Faculty Of Civil & Environmental Engineering Kunsan National University
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Hirano Masashi
Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Ichikawa Nobuhiro
College Of Pharmaceutical Sciences Ritsumeikan University
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Ichikawa Nobuhiro
熊本県立大学 環境共生学部
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石橋 康弘
Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Arizono K
Prefectural Univ. Kumamoto Kumamoto Jpn
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Arizono Koji
Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Arizono K
Faculty Of Pharmaceutical Sciences Nagasaki University
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Hirano Masashi
Faculty Of Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Takao Y
Faculty Of Environmental Studies Nagasaki University
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Takao Yuji
Faculty Of Environmental Studies Nagasaki University
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Yamauchi Ryoko
Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
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Koga Minoru
Environmental and Symbiotic Sciences, Prefectural University of Kumamoto
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Kim Joon-woo
Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Koga Minoru
Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Yamauchi Ryoko
Environmental And Symbiotic Sciences Prefectural University Of Kumamoto
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Ishibashi Hiroshi
Graduate School Of Science And Technology Nagasaki University
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Koga Minoru
Environmental And Symbiotic Sciences Prefectural Univ. Of Kumamoto
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Takao Yuji
Faculty of Environmental Sciences
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