STUDY ON STRUCTURE-ACTIVITY RELATIONSHIP USING MOLECULAR ORBITAL METHOD (PM3)
スポンサーリンク
概要
著者
-
竹内 洋文
50周年誌編集小委員会
-
Takeuchi Yoshikazu
Lab. Of Clinical Pharmaceutics Fac. Of Pharmaceutical Sciences Kobe Gakuin Univ.
-
Yamato M
Okayama Univ. Science Okayama Jpn
-
Yamato M
Faculty Of Science Okayama University Of Science
-
TAKEUCHI Yasuo
Faculty of Pharmaceutical Sciences, Okayama University
-
Yamaoka Takashi
Pharmacology Research Laboratories Dainippon Sumitomo Pharma Co. Ltd
-
Takeuchi Y
Research Center Sumitomo Pharmaceuticals Co. Ltd.
-
YAMATO Masatoshi
Faculty of Pharmaceutical Sciences, Okayama University
-
HASHIGAKI Kuniko
Faculty of Pharmaceutical Sciences, Okayama University
-
Hashigaki K
Faculty Of Pharmaceutical Sciences Okayama University
-
Hashigaki Kuniko
Faculty Of Pharmaceutical Sciences Okayama University
-
Yamato Masatoshi
Faculty Of Pharmaceutical Sciences Okayama University
-
Takeuchi Yasuo
Faculty Of Pharmaceutical Sciences Okayama University
-
Hashigaki Kuniko
Faculty Of Pharmaceutical Sciences Okayama University:cancer Chemotherapy Center
関連論文
- The Stability of a Novel Carbapenem Antibiotic, Meropenem (SM-7338), in a Solid State Formulation for Injection
- Continuous Exposure to Low-Dose Cisplatin and Apoptosis(Miscellaneous)
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Transdermal Drug Delivery by Electroporation Applied on the Stratum Corneum of Rat Using Stamp-Type Electrode and Frog-Type Electrode in Vitro
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- Use of Electroporation to Accelerate the Skin Permeability Enhancing Action of Oleic Acid
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Petroselinic Acid and Oleic Acid : Comparison of Enhanced Skin Permeability Relative to Affinity for Saturated Fatty Acids of Stratum Corneum
- Antitumor Effects of a Novel Lipophilic Platinum Complex (SM-11355) against a Slowly-Groing Rat Hepatic Tumor after Intra-Hepatic Arterial Administration
- Asclepic Acid(cis-ω7-Octadecenoic Acid) as a Skin Penetration Enhancer : Its Behavior and Effects on Rat Stratum Corneum and Dermis
- Enhancement of Propylene Glycol Distribution in the Skin by High Purity cis-Unsaturated Fatty Acids with Different Alkyl Chain Lengths Haiving Different Double Bond Position
- Skin Penetration Enhancing Action of cis-Unsaturated Fatty Acids with ω-9,and ω-12-Chain Lengths
- Enhancement of Propylene Glycol Permeation into Rat Dermis Using High-purity Oleic Acid and Subsequent Alteration of the Dermal Protein Structures
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Effects of Fatty Acids, Fatty Amines and Propylene Glycol on Rat Stratum Corneum Lipids and Proteins in Vitro Measured by Fourier Transform Infrared/Attenuated Total Reflection (FT-IR/ATR) Spectroscopy
- Destabilization of Whole Skin Lipid Bio-liposomes Induced by Skin Penetration Enhancers and FT-IR/ATR (Fourier Transform Infrared/Attenuated Total Reflection) Analysis of Stratum Corneum Lipids
- Microgranulation and Encapsulation of Pulverized Pharmaceutical Powders with Ethyl Cellulose by the Wurster Process
- Effect of Additives on Physical Properties of Fine Ethyl Cellulose Microcapsules Prepared by the Wurster Process
- Coating of Pharmaceutical Powders by Fluidized Bed Process. IV. : Softening Temperature of Acrylic Copolymers and Its Relation to Film-Formation in Aqueous Coating
- Coating of Pharmaceutical Powders by Fluidized Bed Process. III. : Aqueous Coating with Ethyl Acrylate-Methyl Methacrylate-2-Hydroxyethyl Methacrylate Copolymer and the Dissolution Properties of the Products
- Coating of Pharmaceutical Powders by Fluidized Bed Process. II. : Microcapsules Produced by Layering of Fine Powder on Coarse Particles and Subsequent Aqueous Enteric Coating
- 粉体工学会の未来を考える
- 創立から25周年までの歩み
- A New Antitumor Agent Amrubicin Induces Cell Growth Inhibition by Stabilizing Topoisomerase II-DNA Complex
- Effect of +36T > C in intron 1 on the glutamine : fructose-6-phosphate amidotransferase 1 gene and its contribution to type 2 diabetes in different populations
- Concise Synthesis of dl-Febrifugine
- Re-revision of the Stereo Structure of Piperidine Lactone, an Intermediate in the Synthesis of Febrifugine
- Synthesis and Antimalarial Activity of Febrifugine Derivatives
- Reaction of N-Acylated Isofebrifugine with Acid
- In vitro Antitumor Activity, Intracellular Accumulation, and DNA Adduct Formation of cis-[((1R,2R)-1,2-Cyclohexanediamine-N,N')bis(myristato)] Platinum (II) Suspended in Lipiodol
- Coating of Pharmaceutical Powders by Fhiidized Bed Process. I. Aqueous Enteric Coating with Methacrylic Acid-Ethylacrylate Copolymer and the Dissolution Behavior of Products(Pharmaceutical)
- Physical Characterization of Erythromycin Dihydrate, Anhydrate and Amorphous Solid and Their Dissolution Properties
- 細粒と粉末の混合に関する研究(第2報)細粒と微粉砕粉末の混合状態
- 細粒と粉末の混合--混合性におよぼす粉末粒子径と付着力の効果 (〔粉体工学会〕夏期シンポジウム特集)
- SNPs in the KCNJ11-ABCC8 gene locus are associated with type 2 diabetes and blood pressure levels in the Japanese population
- No evidence for association of the ENPP1 (PC-1) K121Q variant with risk of type 2 diabetes in a Japanese population
- Synthesis of Acinetobactin
- Infrequent Detectable Somatic Mutations of the RET and Glial Cell Line-derived Neurotrophic Factor (GDNF) Genes in Human Pituitary Adenomas
- Aryl-Aryl Coupling Reaction Using a Novel and Highly Active Palladium Reagent Prepared from Pd(OAc)_2, 1,3-Bis [diphenylphosphino] propane (DPPP), and Bu_3P
- One-Pot Conversion of Allyl Alcohols into Selenochroman Derivatives
- Synthesis of Arnottin I through a Palladium-Mediated Aryl-Aryl Coupling Reaction
- Synthesis and Antitumor Activity of Fused Quinoline Derivatives. V. Methylindolo[3,2-b]quinolines
- Synthese and Antifungal Activity of dl-Griseofulvin and Its Congeners. III
- Synthesis and Antitumor Activity of Fused Quinoline Derivatives. IV. Novel 11-Aminoindolo[3,2-b]quinolines
- Syntheses and Antifungal Activity of dl-Griseofulvin and Its Congeners. II
- MOLECULAR MODIFICATION AND STRUCTURE-ACTIVITY RELATIONSHIP OF ANTITUMOR ACTIVE INDOLOQUINOLINE DERIVATIVES
- Intramolecular Michael Reaction in Diastereoselective Synthesis of dl-Griseofulvin
- STUDY ON STRUCTURE-ACTIVITY RELATIONSHIP USING MOLECULAR ORBITAL METHOD (PM3)
- SYNTHESIS AND ANTITUMOR ACTIVITY OF FUSED TETRACYCLIC QUINOLINE DERIVATIVES
- Synthesis and Structure-Activity Relationships of Antitumor-active Tropolone Derivatives
- The Rate of Cell Growth Is Regulated by Purine Biosynthesis via ATP Production and G1 to S Phase Transition
- The Diels-Alder Reaction Using a Vinyl Sulfoxide Activated by the Participation of a Neighboring Epoxide Group
- Synthesis and Siderophore Activity of Vibrioferrin and One of Its Diastereomeric Isomers
- Total Synthesis of dl-Febrifugine and dl-Isoferifugine
- Total Synthesis of the Siderophore Vibrioferrin
- REACTION OF ETHYL β-ALKYLAMINOCROTONATES IN THE PRESENCE OF ORGANIC ACID
- Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of human hepatoma cells orthotopically implanted in nude rats
- Amrubicin, a novel 9-aminoanthracycline, enhances the antitumor activity of chemotherapeutic agents against human cancer cells in vitro and in vivo
- Amrubicin induces apoptosis in human tumor cells mediated by the activation of caspase-3/7 preceding a loss of mitochondrial membrane potential
- Uptake and Intracellular Distribution of Amrubicin, a Novel 9-Amino-anthracycline, and Its Active Metabolite Amrubicinol in P388 Murine Leukemia Cells
- Cytotoxicity of Amrubicin, a Novel 9-Aminoanthracycline, and Its Active Metabolite Amrubicinol on Human Tumor Cells
- Tumor-selective Distribution of an Active Metabolite of the 9-Aminoanthracycline Amrubicin
- In vivo Efficacy and Tumor-selective Metabolism of Amrubicin to Its Active Metabolite
- Expression of somatostatin receptor subtypes and growth inhibition in human exocrine pancreatic cancers
- ASYMMETRIC SYNTHESES OF TETRAHYDROISOQUINOLINE AND TETRAHYDRO-β-CARBOLINE DERIVATIVES