Constituents of the Chinese Crude Drug "Wujiapi". IX. Structure of Glycoside H_2,a Potentiator of NGF-mediated Nerve Fiber Outgrowth

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概要

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• Glycoside H_2,C_<56>H_<92>O_<25>, [α]D -25.9°(MeOH), which causes marked potentiation of the effect of NGF (nerve growth factor), was isolated from Bei-Wujiapi (the cortex of Periploca sepium BGE., Asclepiadaceae) and its chemical structure was established to be ⊿^5-pregnene-3β, 16α, 20α-triol 3-O-[2-O-acetyl-β-D-digitalopyranosyl (1→4)-β-D-cymaro-pyranoside] 20-O-[β-D-glucopyranosyl (1→6)-β-D-glucopyranosyl (1→2)-β-D-digitalopyranoside] (1).

• 公益社団法人日本薬学会の論文
• 1980-01-25

著者

• 庄司 順三

  School Of Pharmaceutical Sciences Showa University

• 佐久間 聖一

  School of Pharmaceutical Sciences, Showa University

• 川西 幸子

  School Of Pharmaceutical Sciences Showa University

• 佐久間 聖一

  School Of Pharmaceutical Sciences Showa University

• 庄司 順三

  昭和大学

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