Drug-induced Histological Changes and Its Consequences on the Permeability of the Small Intestinal Mucosa. I. EDTA, Tetracycline, and Sodiun Laurylsulfate
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概要
- 論文の詳細を見る
Acute effect of EDTA-2Na, tetracycline-HCl, and Sodium laurylsulfate on the permeability of the rat small intestine was examined histologically using light microscope and scanning electron microscope. Specimens were obtained from the proximal small intestine after recirculation of the physiological buffer solution of the test compounds through the entire rat small intestine. It was observed that although the remarkable facilitating effect in the absorption of otherwise poorly absobable compounds reported in the literature was common, histological changes were different each other.
- 公益社団法人日本薬学会の論文
- 1972-06-25
著者
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灘井 種一
摂南大・薬
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瀬崎 仁
摂南大・薬
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灘井 種一
摂南大薬
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瀬崎 仁
Faculty Of Pharmaceutical Sciences Kyoto University
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立松 晃
名城大学薬学部
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立松 晃
Faculty of Pharmaceutical Science, Meijo University
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