薬物相互作用に関するPharmacokinetics : 血漿中のChlorzoxazoneの濃度変化におよぼすZoxazolamineの影響
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概要
- 論文の詳細を見る
The effect of zoxazolamine on plasma concentration of chlorzoxazane was examined pharmacokinetically. Zoxazolamine decreased the distribution and elimination rate constants of chlorzoxazone. The mechanism proposed for it is the direct effect of complex formation between chlorzoxazone and zoxazolamine as suggested by Poole, et al. and competitive inhibition for oxidative hydroxylation of chlorzoxazone in the liver.
- 公益社団法人日本薬学会の論文
- 1974-10-25
著者
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崎谷 陽子
Faculty of Pharmaceutical Sciences, Tokushima Bunri University
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粟津 荘司
東京大学薬学部
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花野 学
東京大学薬学部
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野上 寿
東京大学薬学部
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Sakiya Y
Tokushima Bunri Univ. Tokushima Jpn
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崎谷 陽子
Faculty Of Pharmaceutical Sciences Tokushima Bunri University
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崎谷 陽子
昭和薬科大学
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花野 学
College Of Pharmacy Nihon University
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