卵黄レシチンと高級アルコールの混合単分子膜中における分子間相互作用

概要

論文の詳細を見る
Mixed monolayers of egg lecithin (EYPC) with myristyl alcohol (C_<14>OH), cetyl alcohol (C_<15>OH) or stearyl alcohol (C_<18>OH) were spread at air-water interface. The surface pressure mean area (F-A) curves for the mixed monolayers were obtained. F-A curves of the mixed monolayers followed the equations of state of virial type : FA/kT=c+b/A. For C_<18>OH-EYPC and C_<16>OH-EYPC systems except for those of low high alcohol concentration, each FA/kT vs. 1/A plot showed a break point. Limiting areas obtained by extraporating the plots to FA/kT=0 showed that the mixed monolayers of EYPC and C_<14>OH or C_<16>OH were expanded although the mixed monolayers of EYPC and C_<18>OH were rather condensed. It was concluded that attractive force between hydrocarbonchains of C_<14>OH or C_<16>OH was decreased by EYPC. Desorption of C_<14>OH from the monolayers under constant area was studied. The desorption rate of C_<14>OH was enhanced by the addition of a small amount of EYPC and practically depressed by the addition of equal or more moles of EYPC. It was concluded that a small amount of EYPC made C_<14>OH molecules to be in high energy state.
公益社団法人日本薬学会の論文
1987-09-25