A NEW STATISTICAL PROCEDURE OF INTERVAL HYPOTHESIS TESTING FOR BIOEQUIVALENCE STUDIES
スポンサーリンク
概要
- 論文の詳細を見る
A simplified procedure of interval hypothesis testing was investigated and established for bioequivalence studies. The characteristics of this procedure were compared with those of other statistical procedures.
- 社団法人日本薬学会の論文
- 1995-01-15
著者
-
後藤 茂
Faculty Of Pharmaceutical Sciences Kyushu University
-
大木 俊光
Kawanishi Pharma Research Institute, Nippon Boehringer Ingelheim Co., Ltd.
-
鈴木 徳治
Faculty of Pharmaceutical Sciences, Chiba University
-
鈴木 徳治
千葉大 薬
-
鈴木 徳治
千葉大学薬学部
-
鈴木 徳治
Faculty Of Pharmaceutical Sciences Chiba University
-
大木 俊光
Kawanishi Pharma Research Institute Nippon Boehringer Ingelheim Co. Ltd.
-
Goto Sigeru
Facultyof Pharmaceutical Sciences Kyushu University
-
後藤 茂
Faculity of Pharmaceutical Sciences, The University of Tokushima
関連論文
- Transdermal Delivery of Theophylline Using an Ethanol/Panasate 800-Ethylcellulose Gel Preparation
- Relationship between Lipophilicity and Skin Permeability of Various Drugs from an Ethanol/Water/Lauric Acid System
- Effect of Hydrophilic and Lipophilic Vehicles on Skin Permeation of Tegafur, Alclofenac and Ibuprofen with or without Permeation Enhancers
- Evaluation of Enteric Coated Tablet Sensitive to Pancreatic Lipase. II. In Vivo Evaluation
- In Vivo Microdialysis for the Transdermal Absorption of Valproate in Rats
- Studies on Pyrone Derivatives. VI. On the Reaction between Dehydroacetic Acid and Several Ammonium Salts in Solution
- On Reaction between Dehydroacetic Acid and Ammonium Salts in Solution
- A NEW STATISTICAL PROCEDURE OF INTERVAL HYPOTHESIS TESTING FOR BIOEQUIVALENCE STUDIES
- In Vivo Microdialysis for Pharmacokinetic Investigations : A Plasma Protein Binding Study of Valproate in Rabbits
- Preparation and Evaluation of Suppositories for RK-28 (a New Radiosensitizer) Using Rabbits
- Pharmacokinetics of RK-28 (a New Radiosensitizer) and Pharmaceutical Design of a Suppository Form Using Rats
- Transport of Aspirin and Its Metabolites through Human Erythrocyte Membrane
- Preparation and Evaluation of Eudragit Gels. V. Rectal Gel Preparations for Sustained Release and Avoidance of First-Pass Metabolism of Lidocaine
- Effect of Sodium Valproate (VPA) on Cerebral Amino Acids : Mechanism of γ-Aminobutyric Acid (GABA) Elevation and Possible Causal Relation of VPA-Induced Encephalopathy and Glutamine Level
- Rate of Gastric Emptying of Phenol Red in a Rabbit
- Kinetics of Solvolyses of Various N, N'-Dialkyl-N-nitrosoureas in Neutral and Alkaline Solutions
- Effect of Combination of Pharmaceuticals on Gastrointestinal Absorption. III. Combination of Aminopyrine and Barbital. (1)
- Kinetics of Reaction of Dehydroacetic Acid. V. Reaction with Primary Amines. (3)
- Kinetics of Conversion of Diacetylacetone in Aqueous Solution
- Effect of Combination of Pharmaceuticals on Gastrointestinal Absorption. II. Combination of Caffeine with Non-absorbable Drugs
- Effect of Combination of Pharmaceuticals on Gastrointestinal Absorption. I. Combination of Caffeine with a Few Absorbable Drugs
- Colloid Chemical Researches on Suspensions in Pharmacy. III. On Rheological Behavior in Rancid Peanut Oil-Aluminum Stearate System.
- Optimization of Preparative Conditions for Polylactide (PLA) Microspheres Containing Ovalbumin
- Oral Delivery of Poly (lactide-co-glycolide) Microspheres Containing Ovalbumin as Vaccine Formulation : Particle Size Study
- In Vivo Release of Water-Soluble Drugs from Stabilized Water-in-Oil-in-Water (W/O/W) Type Multiple Emulsions Following Intravenous Administrations Using Rats
- Enhancement Effect of an Ethanol/Panasate 800 Binary Vehicle on Anti-inflammatory Drug Permeation across Excised Hairless Mouse Skin
- Utility of Mixture of Commercially Available Polymers as Constituents of Sustained-Release Microcapsules Containing Cefadroxil or Theophylline
- Biopharmaceutical Evaluation of Sustained-Release Ethylcellulose Microcapsules Containing Amoxicillin Using Beagle Dogs
- Biopharmaceutical Evaluation of Sustained-Release Ethylcellulose Microcapsules Containing Cefadroxil and Cephradine Using Beagle Dogs
- 2-(3-Pyridyl)thiazolidine-4-carboxamide Derivatives. II. Structure-Activity Relationships and Active Configuration of 2-(3-Pyridyl)thiazolidine-4-carboxamides as Platelet-Activating Factor Receptor Antagonists
- Plasma Protein Binding, Renal Clearance, and Pharmacokinetics of Diuretics in Rabbits
- Binding of Diuretics to Human Serum Albumin and to Human Serum from Healthy Adults and Patients with Renal Failure
- Synthesis and Biological Activity of the Metabolites of N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline Fumarate (SK-946)
- Synthesis of (1-Azabicyclo[3.3.0]octanyl)methyl-Substituted Aromatic Heterocycles and Their Muscarinic Activity
- Determination of Phenylbutazone and Its Metabolites in Plasma by Gas-Liquid Chromatographic Procedure
- Metabolism and Cytotoxieity of Hydrazine in Isolated Rat Hepatocytes(Biological)
- HEPATOTOXICITY OF HYDRAZINE IN ISOLATED RAT HEPATOCYTES
- An Improved Synthesis of Butyl 4-[(4-Amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate (AU-224)
- Structure-Activity Relationship(SAR)Studies on Oxazolidinone Antibacterial Agents.1. Conversion of 5-Substituent on Oxazolidinone
- 薬物のBioavailability (最新薬物療法manual--投薬の基本と治療プログラム) -- (薬物投与の基礎理論--PharmacokineticsとPharmacodynamics)
- 製剤の進歩による新しい薬剤 (新しい薬--その開発と臨床応用)
- Structure-Activity Relationship of a New Series of Tricyclic Monoamine Oxidase Inhibitors of Pentanthrene Type
- Effect of Humidity Aging on Disintegration, Dissolution and Cumulative Urinary Excretion of Calcium p-Aminosalicylate Formulations(Pharmaceutical)
- Evaluation of Enteric Coated Tablet Sensitive to pancreatic Lipase. I. In Vitro Disintegration Test
- Characterization of the Neurochemical Effects of N-[2-(1-azabicyclo[3,3,0]octan-5-yl)ethyl]2-nitroaniline fumarate (SK-946) as a Cognition Activator
- Evaluation of Isonicotinoyl-γ-Aminobutyric Acid (GABA) and Nicotinoyl-GABA as Pro-drugs of GABA
- Simple Method for Repetitive Blood Sampling in a Self-Controlled Design in the Rat
- Drug Absorption and Metabolism Studies by Use of Portal Vein Infusion in the Rat. II. Influence of Dose and Infusion Rate on the Bioavailability of Propranolol
- Pharmacokinetic Analysis of Blood Level Data interpreted by a Two-Compartment Model
- Drug Absorption and Metabolism Studies by Use of Portal Vein Infusion in the Rat. I. Pyloric Vein Cannulation and Its Application to Study of First-Pass Effect on Bioavailability of Propranolol
- インスリンの消化管吸収に対するキモトリプシン阻害剤FK-448の増強作用
- New Approach to the Hepatic First-Pass Effect by Whole-Body Autoradiography
- Immunoliposome-Mediated Gene Transfer into Cultured Myotubes
- Examination of Local Anti-inflammatory Activities of New Steroids, Hemisuccinyl Methyl Glycolates
- アドレナリンβ-遮断薬o-[3-(tert-Butylamino)-2-hydroxypropoxy]benzonitrile(Bunitrolol)の代謝に及ぼす投与経路の影響
- Effect of Environmental Temperature on the Elimination of Theophylline
- DETECTION OF A NEW SERIES OF MONOAMINE OXIDASE INHIBITORS
- Effect of Modification of Albumin on Tolbutamide-Serum Albumin Binding
- Binding of Sulfonylurea-related Compounds with Bovine Serum Albumin
- Biopharmaceutical Evaluation of Gelatin Microcapsules of Sulfonamides
- Preparation and Evaluation of Gelatin Microcapsules of Sulfonamides
- マイクロコンピュータを用いたシンプレックス法による薬物速度論的パラメータの推定
- Modification by Fluoride, Bromide, Iodide, Thiocyanate and Nitrite Anions of Reaction of a Myeloperoxidase-H_2O_2-Cl^- System with Nucleosides
- Effects of Fluvastatin and Its Major Metabolites on Low-Density Lipoprotein Oxidation and Cholesterol Esterification in Macrophages
- Fluvastatin, an HMG-CoA Reductase Inhibitor, Protects LDL from Oxidative Modification in Hypercholesterolemic Rabbits
- In Vitro Inhibitory Effects of the Optical Isomers and Metabolites of Fluvastatin on Copper Ion-Induced LDL Oxidation
- An in Vitro Study of the Hydroxyl Radical Scavengin Property of Fluvastatin, and HMG-CoA Reductase Inhibitor
- 生物学的同等性の判定における仮説検定法, 区間推定法, 及びBayes流の解析法の比較
- 初回通過効果 : 生物学的利用性に影響する要因
- Inhibitory Effects of Fidarestat on Aldose Reductase and Aldehyde Reductase Activity Evaluated by a New Method Using HPLC with Post-column Spectrophotometric Detection
- 2-(3-Pyridyl)thiazolidine-4-carboxamide Derivatives. III. Synthesis of Metabolites and Metabolism of 2-(3-Pyridyl)thiazolidine-4-carboxamides YM461 and YM264 as Platelet-Activating Factor (PAF) Receptor Antagonists
- Synthesis of the Selective 5-Hydroxytryptamine 4 (5-HT_4) Receptor Agonist (+)-(S)-2-Chloro-5-methoxy-4-[5-(2-piperidylmethyl)-1,2,4-oxadiazol-3-yl]aniline
- Intramolecular Oxymercuration with Mercuric Triflate
- Mercuric Triflate-TMU Catalyzed Hydration of Terminal Alkyne to give Methyl Ketone under Mild Conditions
- Effects of N-[2-(1-Azabicyclo[3,3,0]octan-5-yl)ethyl]2-nitroaniline Fumarate (SK-946), a Novel Cognition Activator, on Learning and Memory in Rodent Models
- Novel 5-Hydroxytryptamine 4 (5-HT_4) Receptor Agonists. Synthesis and Gastroprokinetic Activity of 4-Amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro-2-methoxybenzamides
- Effect of the Cholesterol Content on the Stability of Liposomes in the Blood Circulation
- Biopharmaceutical Evaluation of Gelatin Microcapsules of Several Oral Antibiotics
- Preparation and Dissolution Pattern of Eudragit RS Microcapsules Containing Ketoprofen
- Effect of repeated administration of propranolol on liver metabolism and its factors.
- Effect of repeated administration of propranolol on non-linear first pass metabolism.
- Strain specificity of metabolism of propranolol and lidocaine in rats.
- Problems with pharmacotherapy in elderly patients. 1. Specificity of variation in metabolic activities accompanying senile change.
- タイトル無し