Synthesis and Biological Activity of the Metabolites of N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline Fumarate (SK-946)

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概要

• 論文の詳細を見る

• Three metabolites of N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline fumarate (SK-946), a novel central muscarinic cholinergic receptor agonist, were prepared to confirm their proposed structures, and tested for muscarinic receptor affinity in vitro.

• 社団法人日本薬学会の論文
• 1999-06-15

著者

• 斎藤 徹

  Faculty Of Pharmaceutical Sciences Kanazawa University

• Ikami T

  Miki Corp. Nishinomiya Jpn

• Suzuki T

  Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• SUZUKI Tomoo

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• IKAMI Takao

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• INAGAKI Hideaki

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• HAMAJIMA Hitoshi

  Drug Discovery Research Laboratory, Sanwa Kagaku Kenkyusho Co. Ltd.,

• 鈴木 徳治

  千葉大 薬

• Suzuki T

  Laboratory Of Biopharmaceutics Faculty Of Pharmaceutical Sciences Chiba University

• UESAKA Hiroshi

  Drug Development Laboratory, Sanwa Kagaku Kenkyusho Co., Ltd.,

• HORI Kohsuke

  Drug Development Laboratory, Sanwa Kagaku Kenkyusho Co., Ltd.,

• Saito T

  Research And Development Headquarters Hokurikit Seiyaku Co. Ltd.

• Saito Takako

  Research And Development Laboratories Maruho Co. Ltd.

• Ikami Takao

  Drug Discovery Research Department Sanwa Kagaku Kenkyusho Co. Ltd.

• Suzuki Toshikazu

  Discovery Research Laboratory Tanabe Seiyaku Co. Ltd.

• Hori Kohsuke

  Drug Development Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• Uesaka H

  Drug Development Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• Suzuki T

  Research Unit Of Pharmaceutics College Of Pharmacy Nihon University

• Sugihara T

  Faculty Of Pharmaceutical Sciences Tokushima Bunri University

• Saito T

  Research And Development Laboratories Maruho Co. Ltd.

• Inagaki Hideaki

  Drug Discovery Research Department Sanwa Kagaku Kenkyusho Co. Ltd.

• Inagaki Hideaki

  Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• Hamajima Hitoshi

  Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• Hamajima Hiroshi

  Drug Discovery Research Laboratory, Sanwa Kagaku Kenkyusho Co., Ltd.,

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