N-[2-(1-AZABICYCLO[3.3.0]OCTAN-5-YL)ETHYL]-2-NITROANILINE, A POTENT MUSCARINIC AGONIST

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概要

• 論文の詳細を見る

• The muscarine receptor agonist SK-946,and aniline derivative with a characteristic bicyclo amine, was found. We describe a new synthetic method for 1-azabicyclo[3.3.0]octane and describe the biological activity of SK-946.

• 社団法人日本薬学会の論文
• 1997-07-15

著者

• KATAOKA Tadashi

  Gifu Pharmaceutical University

• SUZUKI Tomoo

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• OKA Mituru

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• MAEDA Kouji

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• FURUSAWA Kenichi

  Development Department, Sanwa kagaku Kenkyusho Co., Ltd.,

• MITANI Takahiko

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• OKA Mitsuru

  Drug Discovery Research Laboratory, Sanwa Kagaku Kenkyusho Co., Ltd.,

• Furusawa K

  Pharmaceutical Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

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• N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline, A Potent Muscarinic Agonist.
• N-[2-(1-AZABICYCLO[3.3.0]OCTAN-5-YL)ETHYL]-2-NITROANILINE, A POTENT MUSCARINIC AGONIST
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• A New Entry to Enantioselective Synthesis of α-Nethylene-β-hydroxy Ketones by the Chalcogeno-Baylis-Hillman Reaciton
• Serotonin 5-HT_4 Receptor Agonistic Activity of the Optical Isomers of (±)-4-Amino-N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-5-chloro-2,3-dihydro-2-methylbenzo[b]furan-7-carboxamide
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