A Convenient and Efficient Synthesis of Sialyl Lewis X

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概要

• 論文の詳細を見る

• A convenient synthesis of the sialyl Lewis X (sLe^x) tetrasaccharide, NeuAcα2-3Galβ1-4 (Fucα1-3) GlcNAc (8), as a carbohydrate ligand for selectins is described. The key step is the reaction between NeuAcα2-3GalSMe (5) as a glycosyl donor and the suitably protected Fucα1-3GlcNAc derivative (4) as the glycosyl acceptor by using dimethyl (methylthio) sulfonium triflate (DMTST) as the promoter.

• 社団法人日本農芸化学会の論文
• 1998-03-23

著者

• HASEGAWA Akira

  Department of Quantum Science and Energy Engineering, Tohoku University

• 岩田 憲幸

  桐蔭横浜大学工学部

• KISO Makoto

  Department of Bioorganic Chemistry Gifu University

• Kiso Makoto

  The Foundation For Ume Research Gakuen

• Iwata Noriyuki

  Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• ISHIDA Hideharu

  Department of Applied Bio-organic Chemistry, Gifu University

• Ikami T

  Miki Corp. Nishinomiya Jpn

• Kiso M

  The Foundation For Ume Research Gakuen

• Hasegawa A

  Niigata Univ. Niigata

• Hasegawa A

  Department Of Applied Bioorganic Chemistry Gifu University

• IKAMI Takao

  Drug Discovery Research Department, Sanwa Kagaku Kenkyusho Co., Ltd.,

• BABA Kunihisa

  Drug Discovery Research Laboratory, Sanwa Kagaku Kenkyusho Co. Ltd.,

• HAMAJIMA Hitoshi

  Drug Discovery Research Laboratory, Sanwa Kagaku Kenkyusho Co. Ltd.,

• Kiso Makoto

  ニュージーランド

• Kiso Makoto

  Department Of Applied Bio-organic Chemistry Gifu University

• Kiso Makoto

  Faculty Of Appleid Biological Science Gifu University

• Ishida H

  Hiroshima Univ. Hiroshima

• Ishida H

  Osaka Prefecture Univ. Osaka

• Ishida Hideharu

  Faculty Of Appleid Biological Science Gifu University

• Ishida Hideharu

  Department Of Applied Bio-organic Chemistry Gifu University

• Ikami Takao

  Drug Discovery Research Department Sanwa Kagaku Kenkyusho Co. Ltd.

• Hasegawa Akira

  Department Of Applied Bioorganic Chemistry Gifu University

• Hasegawa Akira

  Department Of Physics Saga University

• Baba Kunihisa

  Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• Kitagawa Masayuki

  Department Of Applied Bioorganic Chemistry Gifu University

• Ito T

  Tottori Univ. Tottori Jpn

• Iwata N

  Dong‐eui Univ. Busan Kor

• Matsuoka Koji

  Department Of Functional Materials Science Saitama University

• Hasegawa Akira

  Department Of Anesthesiology And Intensive Care Medicine Oita University Faculty Of Medicine

• Hamajima Hitoshi

  Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.

• Hasegawa Akira

  Departmemt Of Information And Imaging Sciences Faculty Of Engineering Chiba University

• Kiso Makoto

  Department Of Applied And Bio-organic Chemistry Gifu University

• Ishida Hideharu

  Department Of Applied And Bio-organic Chemistry Gifu University

• KISO Makoto

  Department of Agricultural Chemistry, Gifu University

• ISHIDA Hideharu

  Department of Agricultural Chemistry, Gifu University

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