Synthesis and Biological Activity of the Lipophilic Derivatives of N-Acetyl-1-thiomuramoyl-L-alanyl-D-isoglutamine(Organic Chemistry)

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概要

• 論文の詳細を見る

• A variety of the lipophilic derivatives at C-1 and C-6 in N-[2-O-(2-acetamido-2,3-dideoxy-1-thio-β-D-glucopyranose-3-yl)-D-lactoyl]-L-alanyl-(N^1-fatty acyl)-D-isoglutamine methyl esters were synthesized from 2-N-acetyl-1 -,S-acetyl-4,6-O-isopropylidene-1-thiomuramoyl-L-alanyl-D-isogluta-mine methyl ester. Their immunoadjuvant activity in guinea-pigs, and the protective effect in mice infected with Escherichia coli(E-77156) were examined.

• 社団法人日本農芸化学会の論文
• 1986-08-23

著者

• HASEGAWA Akira

  Department of Quantum Science and Energy Engineering, Tohoku University

• KISO Makoto

  Department of Bioorganic Chemistry Gifu University

• Kiso Makoto

  The Foundation For Ume Research Gakuen

• Hasegawa A

  Department Of Applied Bioorganic Chemistry Gifu University

• HARA Shuichi

  Department of Electronic Engineering, Faculty of Engineering, Kobe University

• Azuma Ichiro

  Institute of Immunological Science, Hokkaido University

• Kiso Makoto

  ニュージーランド

• Kiso Makoto

  Department Of Applied Bio-organic Chemistry Gifu University

• Azuma I

  Hakodate National Coll. Of Technol. Hakodate Jpn

• Azuma Ichiro

  Institute Of Immunological Science Hokkaido University

• Hasegawa Akira

  Department Of Applied Bioorganic Chemistry Gifu University

• Hara S

  National Research Institute Of Brewing

• Hara Shuichi

  Department Of Electronic Engineering Faculty Of Engineering Kobe University

• Kitagawa Masayuki

  Department Of Applied Bioorganic Chemistry Gifu University

• Azuma Ichiro

  Institute Of Immunological Cience

• Hasegawa Akira

  Departmemt Of Information And Imaging Sciences Faculty Of Engineering Chiba University

• Kiso Makoto

  Department Of Applied And Bio-organic Chemistry Gifu University

• KISO Makoto

  Department of Agricultural Chemistry, Gifu University

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