Synthesis of N-[2-O-(2-Acetamido-1,5-anhydro-2,3-dideoxy-D-glucitol-3-yl)-D-lactoyl]-L-alanyl-D-isoglutamine (1-Deoxy-MDP) and Some of Its Lipophilic Analogs, and Their Immunoadjuvant Activities(Organic Chemistry)

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概要

• 論文の詳細を見る

• N-[2-O-(2-Acetamido-1,5-anhydro-2,3-dideoxy-D-glucitol-3-yl)-D-lactoyl]-L-alanyl-D-isoglutamine (1-deoxy-MDP) and its lipophilic analogs were synthesized from 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl chloride. The immunoadjuvant activity was examined in order to clarify the structural requirements of the carbohydrate moiety and the effects of the lipophilic character for this activity in N-acetylmuramoyl-L-alanyl-D-isoglutamine (MDP).

• 社団法人日本農芸化学会の論文
• 1986-07-23

著者

• HASEGAWA Akira

  Department of Quantum Science and Energy Engineering, Tohoku University

• KISO Makoto

  Department of Bioorganic Chemistry Gifu University

• Kiso Makoto

  The Foundation For Ume Research Gakuen

• Hasegawa A

  Department Of Applied Bioorganic Chemistry Gifu University

• Azuma Ichiro

  Institute of Immunological Science, Hokkaido University

• Kiso Makoto

  ニュージーランド

• Kiso Makoto

  Department Of Applied Bio-organic Chemistry Gifu University

• Azuma I

  Hakodate National Coll. Of Technol. Hakodate Jpn

• Azuma Ichiro

  Institute Of Immunological Science Hokkaido University

• SEKI Eiji

  Department of Agricultural Chemistry, Gifu University

• SEKI Eiji

  Senmi Ekisu Co.

• Hasegawa Akira

  Department Of Applied Bioorganic Chemistry Gifu University

• Seki Eiji

  Department Of Agricultural Chemistry Gifu University

• Kitagawa Masayuki

  Department Of Applied Bioorganic Chemistry Gifu University

• HIOKI Yuichi

  Department of Agricultural Chemistry, Gifu University

• Hioki Yuichi

  Department Of Agricultural Chemistry Gifu University

• Azuma Ichiro

  Institute Of Immunological Cience

• Hasegawa Akira

  Departmemt Of Information And Imaging Sciences Faculty Of Engineering Chiba University

• Kiso Makoto

  Department Of Applied And Bio-organic Chemistry Gifu University

• KISO Makoto

  Department of Agricultural Chemistry, Gifu University

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