Application of Sweet Potato Fiber to Skin Wound in Rat
スポンサーリンク
概要
- 論文の詳細を見る
In order to introduce a suitable drug mixing base or covering for burns or decubital wounds, the usefulness of fiber extracted from the sweet potato was investigated. The healing effect of the fiber was evaluated by examining the extent of reduction in the size of wounds and changes in the quality of wounds in rats. In contrast to the control, the use of the fiber alone as a wound covering material reduced wounded areas by 21.0% at postoperative day 9,19.5% at day 11,and 18.7% at day 13,and resulted in an obvious increase in the rats' weight. The number of days required for healing in all treated rats was 19 for the fiber groups and over 21 d for the control. In vitro, the fiber indicated excellent absorptive ability for serum and good adhesive ability for a number of proteins. This result suggested that the fiber has favorable properties for healing wounds which contain large amounts of exudate. Our macroscopic findings also indicated that the fiber protected wounds from dryness. These results suggested that sweet potato fiber could be use as a covering material in combination with drugs in skin wound therapy.
- 公益社団法人日本薬学会の論文
- 1996-07-15
著者
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斎藤 徹
Faculty Of Pharmaceutical Sciences Kanazawa University
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SUZUKI Toshio
Department of Animal Science, Faculty of Agriculture, Utsunomiya University
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Sato E
Department Of Pharmaceutical Science Akita University School Of Medicine
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Suzuki T
Drug Discovery Research Laboratory Sanwa Kagaku Kenkyusho Co. Ltd.
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TADA Hitoshi
Department of Pharmaceutical Science, Akita University Hospital
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Suzuki T
Laboratory Of Biopharmaceutics Faculty Of Pharmaceutical Sciences Chiba University
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Saito Takako
Research And Development Laboratories Maruho Co. Ltd.
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SATO ETSUKO
Department of Pharmaceutical Science, Akita University School of Medicine
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SAGAE Yoshinori
Department of Pharmaceutical Science, Akita University Hospital
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Sato Etsuko
Department Of Pharmaceutical Science Akita University School Of Medicine
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Suzuki Toshikazu
Discovery Research Laboratory Tanabe Seiyaku Co. Ltd.
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Sagae Yoshinori
Department Of Pharmaceutical Science Akita University Hospital
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Tada H
Department Of Pharmaceutical Science Akita University School Of Medicine
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Tada Hitoshi
Department Of Pharmaceutical Science Akita University Hospital
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Suzuki T
Research Unit Of Pharmaceutics College Of Pharmacy Nihon University
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Sato Etsuko
Department Of Ophthalmology Japanese Red Cross Nagoya First Hospital
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Suzuki Toshio
Department Of Agronomy Faculty Of Agriculture Tohoku University
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