Purines. LX. Dimroth Rearrangement and Concomitant Hydrolytic Deamination of 7-Alkyl-1-methyladenines
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概要
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The Dimroth rearrangement of 7-alkyl-1-methyladenines (8) to produce 7-alkyl-N^6-methyladenines (9) (63-72% yield) has been found to be accompanied with unusual hydrolytic deaminations to give 7-alkyl-1-methylhypoxanthines (10) (1-3.5%) and/or 7-alkylhypoxanthines (11) (12-22%), when effected in boiling H_2O for 4-70 h. Probable pathways leading to these by-products are proposed.
- 1994-02-15
著者
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斎藤 徹
Faculty Of Pharmaceutical Sciences Kanazawa University
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鈴木 朋子
Faculty Of Pharmaceutical Sciences Kanazawa University
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藤井 澄三
Faculty Of Pharmaceutical Sciences Kanazawa University
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藤井 澄三
金沢大学薬学部
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伊井 陵子
Faculty of Pharmaceutical Sciences, Kanazawa University
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藤井 澄三
Shinshu Univ. Nagano Jpn
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伊井 陵子
Faculty Of Pharmaceutical Sciences Kanazawa University
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