Quinolizidines. XXVI. : A Synthesis of (±)-Deplancheine

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概要

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• A formal racemic synthesis of the Alstonia and Aspidosperma alkaloid deplacheine (12) has been achieved in the form of the synthesis of the tetracyclic methyl ketone 11 through the ""3-acetylpyridine route."" The route started with an initial quaternization of the ketal 5 with 2-(3-indolyl)ethyl bromide and proceeded through the intermediates 7 and 8.

• 公益社団法人日本薬学会の論文
• 1989-10-25

著者

• 藤井 澄三

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 大場 正志

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 笹木 紀子

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 大場 正志

  Kanazawa Univ. Ishikawa Jpn

• Ohba M

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 藤井 澄三

  Shinshu Univ. Nagano Jpn

関連論文

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• Purines. LXVII. An Alternative Synthesis of Adenine 7-Oxide : N-Oxidation of the Adenine Ring Utilizing Blocking/Deblocking at the 1-Position
• Purines. LXVI. Adenine 7-Oxide : Its Synthesis, Chemical Properties, and X-ray Molecular Structure
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• Purines. LI. Synthesis and Biological Activity of Hypoxanthine 7-N-Oxide and Related Compounds
• Purines. L. Synthesis and Antileukemic Activity of the Antibiotic Guanine 7-Oxide and Its 9-Substituted Derivatives
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• Lactams. XI. Construction of Lactam Carbonyl Function in 1,3-Disubstituted Piperidines by Mercuric Acetate-EDTA Oxidation : Effects of Carbonyl and Related Groups at the 3-Position
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