Lactams. XIX. The Alkaline Ferricyanide Oxidation of 1,3-Disubstituted Pyridinium Salts : Effects of Branched Alkyl Groups at the 3-Position
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概要
- 論文の詳細を見る
In the oxidation of 3-substituted 1-methylpyridinium salts (type III) with potassium ferricyanide and KOH at 32℃, the isopropyl and the tert-butyl group at the 3-position were found to orient oxidation to both the 2-(type IV) and the 6-position (type V) in ratios of 71 : 29 and 14 : 86,respectively. In the oxidation of the 1-methyl-3-tert-butyl-pyridinium salt (IIIl), replacement of the 1-methyl group by an aralkyl group along the series benzyl, phenethyl, and 3,4-dimethoxyphenethyl decreased the extent of the 2-pyridone formation along the series.
- 公益社団法人日本薬学会の論文
- 1981-09-25
著者
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藤井 澄三
Faculty Of Pharmaceutical Sciences Kanazawa University
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大場 正志
Faculty of Pharmaceutical Sciences, Kanazawa University
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大場 正志
Kanazawa Univ. Ishikawa Jpn
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Ohba M
Faculty Of Pharmaceutical Sciences Kanazawa University
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平賀 貴志
Faculty Of Pharmaceutical Sciences Kanazawa University
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