HEPATOTOXICITY OF HYDRAZINE IN ISOLATED RAT HEPATOCYTES
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概要
- 論文の詳細を見る
Cytotoxicity of hydrazine (Hz) and acetylhydrazine (AcHz) was investigated using isolated rat hepatocytes. 10^<-4>, 10^<-3> and 10^<-2>M of Hz decreased hepatocellular reduced glutathione (GSH) in a strongly dose-dependent manner, while AcHz showed little effect on the GSH levels at any concentration examined. The results reveal that Hz is more hepatotoxic than AcHz.
- 社団法人日本薬学会の論文
- 1984-02-25
著者
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後藤 茂
Faculty Of Pharmaceutical Sciences Kyushu University
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千堂 年昭
Faculty Of Pharmaceutical Sciences Kyushu University
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大野 浩司
Faculty Of Pharmaceutical Sciences Kyushu University
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野田 浩司
産業医科大学附属病院 薬剤
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野田 浩司
Department Of Geology National Science Museum
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野田 敦子
Faculty of Pharmaceutical Sciences, Kyushu University
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野田 浩司
産業医大・薬剤部
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野田 浩司
Department Of Hospital Pharmacy School Of Medicine University Of Occupational And Environmental Heal
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後藤 茂
Faculity of Pharmaceutical Sciences, The University of Tokushima
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