Preparation and Evaluation of Gelatin Microcapsules of Sulfonamides
スポンサーリンク
概要
- 論文の詳細を見る
A simple microencapsulation of three sulfonamides (sulfanilamide, sulfisomidine and sulfamethizole) was investigated. The preparation is based on dispersion of a gelatinsulfonamide mixture in liquid paraffin, followed by drying and hardening with formalinisopropanol treatment. The microcapsules were recovered as a discrete, free-flowing powder with a particle diameter of 250-840μm. Dissolution of sulfamethizole from microcapsules approximated a zero-order release pattern from 0 to 10-30% dissolution. These microcapsules may be useful for studies related to sustained-release formulation.
- 公益社団法人日本薬学会の論文
- 1983-01-25
著者
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後藤 茂
Faculty Of Pharmaceutical Sciences Kyushu University
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小松 正明
Faculty Of Pharmaceutical Sciences Okayama University
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川田 昌和
Faculty of Pharmaceutical Sciences, Kyushu University
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田川 公造
Faculty of Pharmaceutical Sciences, Okayama University
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田川 公造
Faculty Of Pharmaceutical Sciences Okayama University
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川田 昌和
Faculty Of Pharmaceutical Sciences Kyushyu University
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後藤 茂
Faculity of Pharmaceutical Sciences, The University of Tokushima
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