DETECTION OF A NEW SERIES OF MONOAMINE OXIDASE INHIBITORS
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概要
- 論文の詳細を見る
A new series of monoamine oxidase (MAO) inhibitors structurally analogous to tetrazolo [5,1-a] phthalazine (Tetra-P) was detected using rat brain mitochondrial MAO. In the tricyclic group, naphtetrazole (NTE) indicated a marked potency of MAO inhibition almost equal to that of iproniazid, and naphtriazole (NTR) showed similar potency as did Tetra-P. The nonselective and competitive inhibition for both types, MAO-A and MAO-B, was observed in some Tetra-P analogues.
- 公益社団法人日本薬学会の論文
- 1985-12-25
著者
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後藤 茂
Faculty Of Pharmaceutical Sciences Kyushu University
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野田 敦子
九州大学大学院薬学研究院医療薬科学部門製剤設計学
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野田 敦子
Facutly Of Pharmaceutical Sciences Kyushu University
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野田 浩司
Department Of Geology National Science Museum
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甲斐 麻美子
九州大学薬学部
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野田 敦子
Faculty of Pharmaceutical Sciences, Kyushu University
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甲斐 麻美子
Faculty of Pharmaceutical Sciences, Kyushu University
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野田 浩司
Department Of Hospital Pharmacy School Of Medicine University Of Occupational And Environmental Heal
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後藤 茂
Faculity of Pharmaceutical Sciences, The University of Tokushima
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